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Table 1 Univariate and multivariate analysis of factors associated with death during antituberculous treatment in the district of Manhiça (2011–2012)

From: Poor tuberculosis treatment outcomes in Southern Mozambique (2011–2012)

 

Total analysed

Outcome of treatment

uOR (95 % CI)

p value

aOR (95 % CI)

p value*

 

N#

%

Death N

(%)

Alive N

(%)

Year

 2011

946

48.3

157

16.6

789

83.4

Ref

0.063

Ref

0.87

 2012

1011

51.7

137

13.6

871

86.4

0.79 (0.62–1.01)

1.03 (0.73–1.44)

Age

  < 15

224

11.5

24

10.7

200

89.3

Ref

0.071

Ref

0.093

 15–24

174

8.9

25

14.4

149

85.6

1.40 (0.77–2.54)

1.57 (0.49–5.01)

 25–34

625

32.1

91

14.6

534

85.4

1.42 (0.88–2.29)

1.40 (0.48–4.01)

 35–44

407

20.9

75

18.5

331

81.5

1.89 (1.15–3.09)

1.73 (0.58–5.14)

 45–54

258

13.2

34

13.2

223

86.8

1.27 (0.73–2.22)

1.56 (0.51–4.77)

  > 55

261

13.4

45

17.3

215

82.7

1.74 (1.03–2.97)

2.45 (0.80–7.50)

Sex

 Female

856

43.9

118

13.8

738

86.2

Ref

0.15

Ref

0.041

 Male

1096

56.2

176

16.1

917

83.9

1.20 (0.93–1.54)

1.39 (1.01–1.91)

AFB smear at diagnosis

 Positive

750

51.7

89

11.9

658

88.1

Ref

0.005

Ref

0.009

 Negative

701

48.3

120

17.1

581

82.9

1.52 (1.13–2.05)

1.54 (1.12–2.13)

TB Category

 New Case

1746

89.9

260

14.9

1485

85.1

Ref

0.45

  

 Retreatment

195

10.1

33

16.9

162

83.1

1.16 (0.78–1.73)

  

Type of TB

 Pulmonary

1630

83.4

237

14.6

1390

85.4

Ref

0.17

Ref

0.61

 Extra-pulmonary

325

16.6

57

17.5

268

82.5

1.25 (0.91–1.71)

0.87 (0.52–1.47)

HIV status

 HIV uninfected

540

28.2

45

8.4

494

91.7

Ref

<0.001

Ref

<0.001

 HIV infected not on ART

811

42.4

164

20.2

647

79.8

2.78 (1.96–3.95)

3.50 (2.13–5.74)

 HIV infected on ART

563

29.4

70

12.5

491

87.5

1.56 (1.05–2.32)

1.83 (1.07–3.14)

  1. uOR unadjusted Odd Ratio, aOR Adjusted Odds Ratio, ARV On antiretroviral treatment, AFB acid fast bacilli
  2. *p-value obtained through likelihood ratio test (LRT)
  3. #In some variables (age, age, sex, AFB smear, TB category and TB type and HIV status) there is missing data, because these data were not available