Table 3 GyrA and ParC amino acid substitutions and detection of Class 1 integrons in A. baumannii isolates
Isolate No. | GyrA amino acid changes | ParC amino acid changes | Class 1 integron | bla gene or ISAba1 PCR | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gly -81 | Ser-83 TCA | Ala-84 | Glu-87 | Ser-80 TCG | Glu-84 | integrase | cassette organization | OXA-23 | OXA-24 | OXA-51 | OXA-58 | ISAba1 | IS/OXA-23 PCR | |
LAC–201 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–202 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–203 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–204 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–205 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–206 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–207 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–208 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–209 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–210 | – | Leu TTA | – | – | Leu TTG | – | – | + | – | + | – | + | + | |
LAC–211 | – | Leu TTA | – | – | Leu TTG | – | – | + | – | + | – | + | + | |
LAC–212 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–213 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–214 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–215 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–216 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–217 | – | Leu TTA | – | – | Leu TTG | – | – | + | – | + | – | + | + | |
LAC–218 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–219 | – | Leu TTA | – | – | Leu TTG | – | – | + | – | + | – | + | + | |
LAC–220 | – | Leu TTA | – | – | Leu TTG | – | – | + | – | + | – | + | + | |
LAC–221 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |
LAC–222 | – | Leu TTA | – | – | – | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |
LAC–223 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |
LAC–224 | – | Leu TTA | – | – | Leu TTG | – | – | – | – | + | – | + | ||
LAC–225 | – | Leu TTA | – | – | – | – | – | – | – | + | – | + | ||
LAC–226 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |
LAC–227 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–228 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–229 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–230 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–231 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–232 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–233 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–234 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–235 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | + | – | + | – | + | + |
LAC–236 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |
LAC–237 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |
LAC–238 | – | Leu TTA | – | – | Leu TTG | – | + | aacA4–catB8–aadA1 | – | – | + | – | + | |