Table 3 Prevalence Ratios of Predictors of Asymptomatic Carriage by Log-Binomial Regression Analysis
Characteristic | Prevalence ratio (asymptomatic carriage vs. non-carriage) | 95 % CI | P value |
|---|---|---|---|
Age (per year) | 0.98 | 0.96, 1.01 | 0.18 |
Days from admission to culture (per day) | |||
0–7 | 1.00 | Reference | |
8–14 | 0.79 | 0.33, 1.89 | 0.6 |
15–21 | 1.25 | 0.44, 3.55 | 0.67 |
≥22 | 1.78 | 0.80, 3.97 | 0.16 |
CDI in the previous 90 days | 4.21 | 2.11, 8.40 | <0.001 |
Any antibiotics | 0.93 | 0.48, 1.82 | 0.83 |
Antibiotics in the past 90 days | 2.70 | 1.15, 6.33 | 0.02 |
Antibiotics in the past 30 days | 2.20 | 1.03, 4.73 | 0.04 |
Inhibitory antibiotic activity (vs. non-inhibitory activity) against C. difficile (among antibiotic users) | 0.41 | 0.14, 1.22 | 0.11 |
Piperacillin/tazobactam (vs. non-inhibitory antibiotics only) | 0.14 | 0.02, 1.14 | 0.06 |
Piperacillin/tazobactam (vs. non-inhibitory and or antibiotics in past 90 days) | 0.14 | 0.02, 0.99 | 0.05 |
Comorbidities | |||
Heart disease | 0.64 | 0.31, 1.32 | 0.23 |
Cancer | 1.16 | 0.60, 2.27 | 0.65 |
Diabetes | 0.75 | 0.38, 1.48 | 0.41 |
End stage renal disease | 1.02 | 0.34, 3.10 | 0.97 |
Major surgery | 0.86 | 0.40, 1.82 | 0.69 |
Spinal cord injury | 1.56 | 0.60, 4.03 | 0.36 |