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Table 1 CDI Episodes in 2009 according to the definition used to identify CDI

From: The burden of clostridium difficile infection: estimates of the incidence of CDI from U.S. Administrative databases

Definition

Medicarea

Lab/Rxa

SIDa

Premier

NIS

Positive test + diagnosis + Rx

N/A

N/A

4,623 (72.8)

Diagnosis + Rx within 14 days after hospital discharge or during hospitalization

1,303 (23.4)

1,088 (65.5)

1,347 (21.2)

Diagnosis + Positive test during hospitalization

N/A

N/A

108 (1.7)

Primary diagnosis

994 (17.8)

194 (11.7)

20,894 (30.5)

13 (0.02)

110,553 (32.8)

Diagnosis on admission

338 (6.1)

N/A

N/A

2 (< 0.01)

N/A

Positive test only

N/A

N/A

N/A

205 (3.2)

N/A

Secondary diagnosis

2,941 (52.7)

379 (22.8)

47,546 (69.5)

52 (0.08)

226,012 (67.2)

Total Inpatient CDI

5,576

1,661

68,440

6,350

336,565

Positive test + Diagnosis + Rx within +/−14 days of diagnosis or positive test date(s)

N/A

87 (2.7)

Diagnosis on ≥ 2 service dates + Rx within +/−14 days of diagnosis date(s)

422 (10.4)

409 (12.6)

Positive test + diagnosis within +/−14 days

N/A

6 (0.2)

Positive test + Rx within +/−14 days

N/A

436 (13.4)

Diagnosis + Rx + lab test within +/−14 days of the diagnosis or lab test date(s)

133 (3.3)

148 (4.6)

Diagnosis + Rx within +/−14 days

334 (8.2)

524 (16.1)

Positive test only

N/A

262 (8.1)

Diagnosis only

3,162 (77.6)

1,251 (38.5)

CDI test + Rx

25 (0.6)

129 (4.0)

Total Outpatient CDI

4,076

3,252

  1. aNumber of unique CDI episodes spaced at least 12 weeks apart
  2. Rx = non-topical metronidazole or oral vancomycin therapy