HIV-infected adults | HIV-uninfected controls | |||||
---|---|---|---|---|---|---|
Baseline | Week 8–12 | Week 48 | Baseline | Week 8–12 | Week 48 | |
Measles | ||||||
Presence of protective antibody to measles | ||||||
All | 222/249 (89.2) | 240/249 (96.4) | 234/247 (94.7) | 44/46 (95.7) | 46/46 (100) | 44/46 (95.7) |
Detectable baseline protective antibody to measles | - | 220/222 (99.1) | 219/220 (99.6) | - | 44/44 (100) | 43/44 (97.7) |
No baseline protective antibody to measles | - | 20/27 (74.1) | 15/27 (55.6) | - | 2/2 (100) | 1/2 (50) |
Anti-measles IgG level (mIU/mL) | ||||||
All | 2654 (1132, 4768) | 2771 (1315, 4911) | 2604 (1208, 5061) | 3353.5 (2035, 5834) | 3221.5 (1367, 5232) | 2863.5 (1659, 5164) |
Detectable baseline protective antibody to measles | 2946 (1560, 5082) | 3022.5 (1674, 5225) | 2993 (1572.5, 5291) | 3450.5 (2215, 5970.5) | 3254.5 (1427.5, 5313.5) | 2977 (1720.5, 5508.5) |
No baseline protective antibody to measles | 200 (148, 269) | 616 (289, 2049) | 394 (228, 961) | 137 (129, 145) | 1791.5 (342, 3241) | 965.5 (226, 1705) |
Mumps | ||||||
Presence of protective antibody to mumps | ||||||
All | 42/249 (16.9)* | 176/249 (70.7)** | 182/247 (73.7)*** | 16/46 (34.8)* | 40/46 (87.0)** | 40/46 (87.0)*** |
Detectable baseline protective antibody to mumps | - | 40/42 (95.2) | 42/42 (100) | - | 13/16 (81.3) | 14/16 (87.5) |
No baseline protective antibody to mumps | - | 136/207 (65.7)**** | 140/205 (68.3)***** | - | 27/30 (90)**** | 26/30 (86.7)***** |
Anti-mumps IgG titer (1:xxxx) | ||||||
All | 220 (61, 431) | 1086 (423, 2818) | 886 (457, 1820) | 247 (107, 399) | 1821 (1223, 3375) | 1191.5 (696, 1997) |
Detectable baseline protective antibody to mumps | 1221 (785, 2765) | 2550 (1198, 4523) | 1836.5 (1089, 3443) | 474 (148, 890) | 2280 (1278, 4006) | 1653 (804, 2054.5) |
No baseline protective antibody to mumps | 151 (36, 323) | 923 (337, 2227) | 777 (361, 1391) | 200 (101, 328) | 1695 (1223, 2819) | 1094.5 (629, 1997) |
Rubella | ||||||
Presence of protective antibody to rubella | ||||||
All | 174/249 (69.9) | 244/249 (98.0) | 241/247 (97.6) | 35/46 (76.1) | 46/46 (100) | 46/46 (100) |
Detectable baseline protective antibody to rubella | - | 174/174 (100) | 171/172 (99.4) | - | 35/35 (100) | 35/35 (100) |
No baseline protective antibody to rubella | - | 70/75 (93.3) | 70/75 (93.3) | - | 11/11 (100) | 11/11 (100) |
Anti-rubella IgG level (IU/mL) | ||||||
All | 27 (5, 74) | 51 (27, 90) | 47 (22, 87) | 15 (7, 40) | 47.5 (26, 86) | 37 (21, 61) |
Detectable baseline protective antibody to rubella | 47.5 (23, 99) | 57.5 (27, 103) | 42.5 (22, 91.5) | 35 (21, 55) | 47 (26, 86) | 35 (21, 55) |
No baseline protective antibody to rubella | 1 (1, 1) | 45 (25, 68) | 52 (23, 79) | 1 (1, 7) | 51 (11, 95) | 42 (10, 42) |