From: Treatment outcomes of reduced-dose intravitreal ganciclovir for cytomegalovirus retinitis
Factors | Univariate | Multivariate | ||
---|---|---|---|---|
p | HR (95 % CI) | p | HR (95 % CI) | |
Age younger than 45 years old | 0.054 | 2.04 (0.99–4.17) | 0.062 | 1.96 (0.96–4.00) |
Male | 0.044 | 1.87 (1.02–3.42) | 0.197 | 1.54 (0.80–2.95) |
Induction with intravenous ganciclovir | 0.372 | 0.77 (0.44–1.36) | 0.533 | 0.83 (0.46–1.49) |
Initial CD4 > 100 | 0.467 | 0.68 (0.24–1.92) | ||
Concurrent anti-retroviral therapy | 0.958 | 1.02 (0.55–1.88) | ||
Initial visual acuity of 6/60 or better | 0.312 | 0.74 (0.41–1.33) | ||
No zone 1 involvementa | 0.122 | 0.64 (0.36–1.13) | 0.030 | 1.96 (1.07–3.58) |
Area of retinitis less than 25 % | 0.252 | 0.71 (0.39–1.28) | 0.192 | 0.59 (0.27–1.30) |
No foveal involvement | 0.885 | 0.96 (0.53–1.72) | ||
No disc involvement | 0.670 | 1.15 (0.60–2.22) | ||
Frosted branch angiitis not presented | 0.017 | 2.18 (1.15–4.13) | 0.007 | 2.55(1.30–5.00) |