Skip to main content

Table 3 Univariate and multivariate Cox regression analyses of factors involving healing time

From: Treatment outcomes of reduced-dose intravitreal ganciclovir for cytomegalovirus retinitis

Factors Univariate Multivariate
  p HR (95 % CI) p HR (95 % CI)
Age younger than 45 years old 0.013 2.86 (1.25–6.67) 0.033 2.5 (1.08–5.88)
Male 0.247 1.46 (0.77–2.67) 0.382 1.51 (0.60–3.83)
Induction with intravenous ganciclovir 0.798 1.09 (0.57–2.07) 0.494 1.26 (0.65–2.44)
Initial CD4 > 100 0.287 1.58 (0.68–3.67)   
Concurrent anti-retroviral therapy 0.324 1.43 (0.70–2.92)   
Initial visual acuity of 6/60 or better 0.335 1.42 (0.69–2.92)   
No zone 1 involvement 0.717 1.12 (0.60–2.08) 0.091 0.50 (0.23–1.12)
Area of retinitis less than 25 % 0.258 1.45 (0.76–2.78) 0.500 1.41 (0.52–3.83)
No foveal involvement 0.162 1.64 (0.82–3.29) 0.023 2.65 (1.14–6.11)
No disc involvement 0.345 1.43 (0.68–3.01)   
Frosted branch angiitis not presented 0.007 2.58 (1.29–5.16) 0.003 3.45 (1.52–7.83)
  1. HR hazard ratio, CI confidence interval
  2. aZone 1, lesions located in the area of the retina within 1500 microns from the edge of the optic nerve or within 3000 microns from the centre of the fovea