Method | Sensitivity | Specificity | PPV | NPV | Diagnostic efficiency |
---|---|---|---|---|---|
Gram Stain of Heart Valve Tissue | 26.0 % (15.1–40.6) | 100 % (78.1–100.0) | 100 % (71.7–100.0) | 32.7 % (21.0–46.8) | 45.6 % (33.8–57.4) |
Heart Valve Tissue Culture | 46 % (33.0–59.6) | 100.0 % (83.1–100.0) | 100.0 % (83.1–100.0) | 41.3 % (27.0–56.7) | 60.2 % (50.8–68.0) |
16S Broad Range PCR/Sequencing | 92.0 % (84.6–96.5) | 77.8 % (57.4–90.4) | 92.0 % (84.6–96.5) | 77.8 % (57.4–90.4) | 88.2 % (77.4–94.9) |