Table 1 Baseline characteristics and outcomes of studied children

Number of patients enrolled, n

64

36

100

Male/Female, n (male %)

36/65 (56.3)

20/36 (55.6)

56.0

Age (months)

12 (2–48)

96 (48–180)

36 (2–180)

Body weight (kg)

9.0 (4.0–15.0)

19.0 (13.5–43.0)

10.9 (4.0–43.0)

BMI (kg/m²)

15.4 (11.9–22.0)

13.3 (10.6–20.2)

14.3 (10.6–22.0)

Malnourished, n (%)

18/64 (28.1)

20/36 (55.5)

38.0

Body weight gained (kg)

 after 1 month

0.5 (−0.3–2.5)

0.75 (−7.5–6.0)

0.5 (−7.5–6.0)

 after 3 months

1.3 (−0.8–5.3)

2.0 (−9.0–12.5)

1.5 (−9.0–12.5)

Fast/Slow acetylator status, n (%)^c

35/23 (60 %)

29/5 (85 %)

64/28 (70 %)

HIV positive, n (%)^d

2/61 (3.3 %)

2/35 (5.7 %)

4/96 (4.2 %)

TBM Grade I, n (%)

43/67 (64 %)

16/33 (48 %)

59/100 (59 %)

TBM Grade II, n (%)

12/67 (18 %)

11/33 (33 %)

23/100 (23 %)

TBM Grade III, n (%)

12/67 (18 %)

6/33 (18 %)

18/100 (18 %)

TB diagnosis: Definite, n (%)

3/64 (4.7 %)

3/36 (8.3 %)

6/100 (6.0 %)

TB diagnosis: Probable, n (%)

39/64 (61 %)

27/36 (75 %)

66/100 (66 %)

TB diagnosis: Possible, n (%)

22/64 (34 %)

6/36 (17 %)

28/100 (28 %)

Death, n (%)

10/64 (16 %)

5/36 (14 %)

15/100 (15 %)

Permanent Sequelae, n (%)^e

19/51 (37 %)

8/30 (27 %)

27/81 (33 %)