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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: Naïve-pooled pharmacokinetic analysis of pyrazinamide, isoniazid and rifampicin in plasma and cerebrospinal fluid of Vietnamese children with tuberculous meningitis

Fig. 1

Plasma (open circles) and CSF (grey squares) concentration-time profiles for pyrazinamide stratified for age (<4 years old [left] and > 4 years old [right]). Continuous lines represent the median plasma concentration and broken lines represent the plasma upper and lower quartiles. Black stars represent plasma samples with concentrations below LOQ. Sub-therapeutic threshold of 35 μg/mL; Minimum Inhibitory Concentration (MIC) of 12.5 μg/mL; and Limit of Quantification (LOQ) of 0.2 μg/mL

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BMC Infectious Diseases

ISSN: 1471-2334

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