Hepatitis B in Ghana: a systematic review & meta-analysis of prevalence studies (1995-2015)

Ofori-Asenso, Richard; Agyeman, Akosua Adom

doi:10.1186/s12879-016-1467-5

BMC Infectious Diseases

Table 1 A summary of the descriptive characteristics of included studies

From: Hepatitis B in Ghana: a systematic review & meta-analysis of prevalence studies (1995-2015)

Study No	Author Details	Year of Publication	Design	Region of study	Study population	Age group	Setting	Sample size(n)	Method	HBsAg + (%)	Quality Grade
1	Addai-Mensah et al. [30]	2015	Cross-sectional	Ashanti	Blood donors^b	17–60	Urban	400	Rapid test	6.75 %	Medium
2	Adjei et al. [31]	2006	Cross-sectional	Eastern & Greater Accra	Prison inmates & Officers	17–84	Urban	363	ELISA	14.3 %	High
3	Adjei et al. [32]	2008	Cross-sectional	National (Excludes Upper East & West)	Prison inmates & Officers	16–84	Urban	1811	ELISA	22.1 %	High
4	Allain et al. [33]	2003	Cross-sectional	Ashanti	Blood donors & Patients	16–59	Urban	383	Mixed methods	13.85 %	High
5	Allain et al. [34]	2009	Cross-Sectional	Ashanti	Blood donors	>16 years	Urban	51100	Rapid test	11.3 %	High
6	Allain et al. [35]	2010	Cross-sectional	Ashanti	Blood donors	31.0^a	Urban	11000	Rapid test	14.2 %	High
7	Amidu et al. [36]	2010	Cross-sectional	Upper East	Blood donors	17–58	Urban	4146	Rapid test	12.64 %	Medium
8	Amidu et a.l [37]	2012	Cross sectional	Ashanti	Community screenees	15–38	Urban	783	Rapid test	8.68 %	High
9	Antwi-Baffour et al. [38]	2014	Cross sectional	Greater Accra	Sickle cell patients	n.s	Urban	202	Rapid test	3.50 %	Low
10	Apea-Kubi et al. [39]	2006	Cross-sectional	Greater Accra	Pregnant & non-pregnant women	29.6^a	Urban	517	Rapid test	16.8 %	High
11	Blankson et al. [8]	2005	Case-control	Greater Accra	Cirrhotic & non-cirrhotic patients	15–90	Urban	350	ELISA	14.6 %	High
12	Candotti et al. [40]	2007	Cross-sectional	Ashanti	Pregnant women	n.s	Urban	1368	Rapid test	16.0 %	High
13	Cho et al. [41]	2012	Cross-sectional	Eastern	Pregnant Women	n.s	Urban	1500	Rapid test	10.6 %	High
14	Damale et al. [42]	2005	Cross-sectional	Greater Accra	Parturients (pregnant women)	27.0^a	Urban	638	n.s	10.5 %	Medium
15	Dongdem et al. [43]	2012	Cross-sectional	Northern	Blood donors	20–29 years	Urban	6321	Rapid test	11.5 %	High
16	Ephraim et al. [44]	2014	Cross-sectional	Central	Type 2 Diabetics	n.s	Urban	110	Rapid test	5.50 %	Medium
17	Ephraim et al. [45]	2015	Cross-sectional	Ashanti	Pregnant women	10–40 year	Urban	168	Rapid test	16.0 %	Medium
18	Geretti et al. [46]	2010	Cross sectional	Ashanti	HIV patients	n.s	Urban	838	Mixed methods	16.7 %	High
19	Kubio et al. [47]	2012	Report review	Northern	Blood donors	n.s	Rural	853	n.s	7.50 %	Low
20	Matinson et al. [48]	1996	Cross-sectional	Ashanti	Children	6–18	Rural	803	immunoassay	15.8 %	Medium
21	Matinson et al. [49]	1998	Cross-sectional	Ashanti	Community screenees	. > 1	Rural	1385	immunoassay	20.9 %	Medium
22	Mutocheluh et al. [50]	2014	Cross-sectional	Brong-Ahafo	Blood donors	17–57	Urban	164	ELISA	14.6 %	High
23	Nkrumah et al. [51]	2011	Cross-sectional	Ashanti	Blood donors	26–35 years	Rural	2773	Rapid test	10.53 %	Medium
24	Nsiah et al. [52]	2012	Cross-Sectional	Ashanti	Sickle cell patients	10–18	Urban	330	Immunoassay	3.60 %	Low
25	Owiredu et al. [53]	2012	Cross-sectional	National (all regions)	Blood donors	n.s	Urban	480	Mixed methods	8.13 %	High
26	Owusu-Ofori et al. [54]	2005	Cross-sectional	Ashanti	Blood donors	n.s	Urban	9372	Rapid test	13.4 %	High
27	Rufai et al. [55]	2014	Cross-sectional	Ashanti	Blood donors	16–59	Urban	150	Immunoassay	13.3 %	Medium
28	Sagoe et al. [56]	2012	Cross-sectional	Greater Accra	HIV patients	≥18 years	Urban	138	ELISA	13.0 %	High
29	Sarkodie et al. [57]	2001	Cross-sectional	Ashanti	Blood donors	16–52	Urban	3587	Mixed methods	15.3 %	High
30	Walana et al. [58]	2014	Cross-sectional	Brong-Ahafo	Blood donors	20–49 years	Urban	3402	ICT	9.60 %	Medium

^a average, HBsAg Hepatitis B surface antigen, n.s not specified, VBD Voluntary blood donor, ELISA Enzyme-Linked Immunosorbent assay, ICT immunochromatography, ^bBlood donors is used to represent either voluntary or replacement donors or both

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