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Fig. 5 | BMC Infectious Diseases

Fig. 5

From: A vaccine consisting of Schistosoma mansoni cathepsin B formulated in Montanide ISA 720 VG induces high level protection against murine schistosomiasis

Fig. 5

Th17, Chemotactic, and Growth Stimulating Cytokine levels. IL-17 (P = 0.0433) a, CCL5 (P = 0.0002) b, and GM-CSF (P = 0.0147) c produced 72 h after stimulating splenocytes ex vivo with recombinant Sm-cathepsin B. Splenocytes were isolated from every C57BL/6 mice belonging to each group: Saline control (saline), Montanide ISA 70VG control (Montanide), and Sm-cathepsin B in the presence of Montanide ISA 720 VG (SmCB + Montanide). Cytokine production was analyzed by QUANSYS multiplex ELISA. Geometric means and 95 % confidence intervals are shown. (ns = not significant, *P <0.05, **P <0.01, ***P < 0.001)

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