Validation of western blot for Histoplasma capsulatum antibody detection assay

BMC Infectious Diseases

Table 3 Performance results of serological tests for detection of antibodies against Histoplasma capsulatum

Histoplasmosis	Immunodifusion (ID)^a		Western blot (WB)^a		p-value**	OR
Histoplasmosis	H and M bands	M band	H and M bands	M band	p-value**	OR
Proven (n = 54)	8	36	21	27	0.009	3.88
Provable (n = 64)	2	62	26	38	0.000	21.21
Total (n = 118)	10	98	47	65	0.000	7.08

^aCases non reagent: ID – 10 cases; WB – 6 cases; **p-value < 0.05 (Chi-square Test and Fisher Exact Test)

ISSN: 1471-2334