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Table 4 Prevalence of HBsAg and BCP/PC mutations observed among HBV genotype A and D sequences

From: Hepatitis B infection is highly prevalent among patients presenting with jaundice in Kenya

  Mutation (%)a
Nucleotide mutation Genotype A Genotype D
HBsAg amino acid substitutionsb 11/77 (14) 0
BCP/PC insertion/deletionsc 5/70 (7) 0
C1653T 2/70 (3) 3/9 (33)
A1752C 0 1/9 (11)
T1753V 3/70 (4) 2/9 (22)
A1762T/G1764Ad 23/70 (33) 4/9 (44)
G1809T 65/70 (93) 0
A1811T/C 7/70 (10) 0
C1812T 62/70 (89) 0
C1858T 4/70 (6) 9/9 (100)
G1862T/C 24/70 (34) 0
G1888A 47/70 (67) 0
G1896A 3/70 (4) 4/9 (44)
  1. aGenotype A: 77 and 70 samples could be amplified for HBsAg and BCP/PC sequences, respectively; Genotype D: Sequence was available in both regions for all 9 samples. bThe following substitutions within the antigenic determinant region (amino acids 100–160) of the HBsAg gene were observed: M103I, L109P, I110L, G112R, T114S, T115A, T118K, Q129R, G130N, M133I, F134I/V, P135H, T143M, S155R; csee text; dincludes A1762/A1764 (6 genotype A and 2 genotype D) and T1762/G1764 (3 genotype A)