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Table 2 Laboratory measurements in three patients with plague infection

From: Plague in China 2014—All sporadic case report of pneumonic plague

  Normal range Patient 1 Patient 2 Patient 3
Haemoglobin (g/L) 110–165 206 201  
Total white cells (×109 cells/L) 3 · 5–10 · 0 8 · 9 58  
Neutrophils (×109 cells/L) 1 · 2–6 · 8 5 · 79 41 · 8  
Lymphocytes (×109 cells/L) 1 · 2–3 · 2 2 · 76 10 · 9  
Platelets (×109 cells/L) 150–390 18 162  
Prothrombin time (s) 12–14 24 · 8 15 · 9  
Activated partial thromboplastin time (s) 25–37 53 · 1 67 · 3  
INR 0 · 8–1 · 5 2 · 52 1 · 43  
D-dimer (mg/L) <0 · 3 0 · 2 0 · 2  
Urea (mmol/L) 2 · 5–7 · 5 7 · 9 14 · 8  
Creatinine (μmol/L) 44–135 161 253  
Bilirubin (μmol/L) 3 · 42–20.5 17 · 4 61 · 8  
Total protein (g/L) 60–80 30 60  
Albumin (g/L) 35–50 23 35  
Globulin (g/L) 25–35 7 25  
Alanine aminotransferase (U/L) 0–40 35 · 4 68  
Aspartate aminotransferase (U/L) 0–37 67 479 · 8  
Lactate dehydrogenase (U/L) 109–245 127 585  
Creatinine kinase (U/L) 24–195 146 9868  
C-reactive protein (mg/L) 0–10 73 150  
Glucose (mmol/L) 3 · 9–6 · 1 19 5 · 1  
Ka (mmol/L) 3 · 5–5 · 1 2 · 6 3 · 03  
Na (mmol/L) 135–147 60 114  
Cl (mmol/L) 95–106 40 80  
Ca (mmol/L) 2 · 25–2 · 75 1 · 62 2 · 09  
Urinalysis     
 PH value 5 · 0–7 · 0 5 · 5 5 · 0  
 Protein (mg/dl)   100 100  
 Ketone (mg/dl)   15 Neg  
 Bilirubin (mg/dl)   0 · 5 0 · 5  
 Urobilinogen (mg/dl)   8 4  
 Blood (mg/dl)   Neg 1  
 Leu (leu/ul)   75 Neg  
Bacterial Diagnostic test     
 Microscopy - + + +
 RT-PCR - + + +
 IHA - 1:40 (serum) 1:2560 (serum) 1:160 (tissue fluid) 1:800 (serum)
 rIHA - 1:6400 (nasopharyngeal swab) 1:12800 (sputum) 1:1024 (serum) 1:5120 (serum)
  1. Results for when the patients presented and the patients’ most abnormal result during disease progression are given. If the reading at presentation was the most abnormal reading, only one result is given
  2. As the third patient’s condition was much threated and death in only one hour, the blood sample had not gathered and many laboratory measurements had not received