Table 2 Laboratory measurements in three patients with plague infection
From: Plague in China 2014—All sporadic case report of pneumonic plague
Normal range | Patient 1 | Patient 2 | Patient 3 | |
|---|---|---|---|---|
Haemoglobin (g/L) | 110–165 | 206 | 201 | |
Total white cells (×109 cells/L) | 3 · 5–10 · 0 | 8 · 9 | 58 | |
Neutrophils (×109 cells/L) | 1 · 2–6 · 8 | 5 · 79 | 41 · 8 | |
Lymphocytes (×109 cells/L) | 1 · 2–3 · 2 | 2 · 76 | 10 · 9 | |
Platelets (×109 cells/L) | 150–390 | 18 | 162 | |
Prothrombin time (s) | 12–14 | 24 · 8 | 15 · 9 | |
Activated partial thromboplastin time (s) | 25–37 | 53 · 1 | 67 · 3 | |
INR | 0 · 8–1 · 5 | 2 · 52 | 1 · 43 | |
D-dimer (mg/L) | <0 · 3 | 0 · 2 | 0 · 2 | |
Urea (mmol/L) | 2 · 5–7 · 5 | 7 · 9 | 14 · 8 | |
Creatinine (μmol/L) | 44–135 | 161 | 253 | |
Bilirubin (μmol/L) | 3 · 42–20.5 | 17 · 4 | 61 · 8 | |
Total protein (g/L) | 60–80 | 30 | 60 | |
Albumin (g/L) | 35–50 | 23 | 35 | |
Globulin (g/L) | 25–35 | 7 | 25 | |
Alanine aminotransferase (U/L) | 0–40 | 35 · 4 | 68 | |
Aspartate aminotransferase (U/L) | 0–37 | 67 | 479 · 8 | |
Lactate dehydrogenase (U/L) | 109–245 | 127 | 585 | |
Creatinine kinase (U/L) | 24–195 | 146 | 9868 | |
C-reactive protein (mg/L) | 0–10 | 73 | 150 | |
Glucose (mmol/L) | 3 · 9–6 · 1 | 19 | 5 · 1 | |
Ka (mmol/L) | 3 · 5–5 · 1 | 2 · 6 | 3 · 03 | |
Na (mmol/L) | 135–147 | 60 | 114 | |
Cl (mmol/L) | 95–106 | 40 | 80 | |
Ca (mmol/L) | 2 · 25–2 · 75 | 1 · 62 | 2 · 09 | |
Urinalysis | ||||
PH value | 5 · 0–7 · 0 | 5 · 5 | 5 · 0 | |
Protein (mg/dl) | 100 | 100 | ||
Ketone (mg/dl) | 15 | Neg | ||
Bilirubin (mg/dl) | 0 · 5 | 0 · 5 | ||
Urobilinogen (mg/dl) | 8 | 4 | ||
Blood (mg/dl) | Neg | 1 | ||
Leu (leu/ul) | 75 | Neg | ||
Bacterial Diagnostic test | ||||
Microscopy | - | + | + | + |
RT-PCR | - | + | + | + |
IHA | - | 1:40 (serum) | 1:2560 (serum) 1:160 (tissue fluid) | 1:800 (serum) |
rIHA | - | 1:6400 (nasopharyngeal swab) 1:12800 (sputum) | 1:1024 (serum) | 1:5120 (serum) |