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Table 3 HIV disease characteristics of study participants stratified by Log10 copy-years/mL

From: Viral load monitoring and antiretroviral treatment outcomes in a pediatric HIV cohort in Ghana

Characteristics

Less than 2 AUVLC(Log10 copy-years/mL) (N = 51)

Between 2 and 4 AUVLC(Log10 copy-years/mL) (N = 27)

Greater than 4 AUVLC(Log10 copy-years/mL) (N = 62)

P value*

Overall Follow up time (in years)

4.6 (3.2, 51)a

4.6 (2.8, 27)

4.3 (1.7, 62)

0.96

AUVLCb (copy-years/mL)

52839.09 (200451.75, 51)

334006.10 (963952.93, 27)

142793.89 (360264.57, 62)

 

Number of opportunistic infections

0.7 (0.8, 51)

0.7 (0.6, 27)

0.8 (0.8, 62)

0.78

Number of outpatient sick visits

1.8 (2.1, 51)

2.3 (1.9, 27)

2.6 (2.3, 62)

0.08

Number of hospitalizations

0.9 (0.8, 51)

0.9 (1.1, 27)

0.8 (1.1, 62)

0.44

Number of composite events

3.6 (2.8, 140)

3.2 (2.5, 51)

3.7 (2.3, 27)

0.33

Clinical/Immunological Treatment Failure

   

0.49

Yes

2 (4.2)c

0 (0.0)

4 (6.5)

 

No

46 (95.8)

26 (100.0)

58 (93.5)

 

Opportunistic infections

   

0.90

Yes

27 (52.9)

16 (59.3)

35 (56.5)

 

No

24 (47.1)

11 (40.7)

27 (43.5)

 

Outpatient sick visits

   

0.03

Yes

33 (64.7)

22 (81.5)

53 (85.5)

 

No

18 (35.3)

5 (18.5)

9 (14.5)

 

Hospitalization

   

0.13

Yes

34 (66.7)

14 (51.9)

30 (48.4)

 

No

17 (33.3)

13 (48.1)

32 (51.6)

 

Composite Eventsd

   

0.39

Yes

47 (92.2)

27 (100.0)

57 (91.9)

 

No

4 (7.8)

0 (0.0)

5 (8.1)

 
  1. *The p value was generated using Wilcoxon Rank Sum test and Fisher’s Exact test for continuous and categorical variables, respectively
  2. aMean (STD, N) for continuous variables
  3. bAUVLC, area under viral load curve
  4. cNumber, N(%)for categorical variables
  5. dComposite events, sum of hospitalization, opportunistic infections and outpatient sick visits