| 2003–2007 | 2008–2012 | ||
---|---|---|---|---|
 | n/N | % (95 % CI) | n/N | % (95 % CI) |
Overall MTCT rate | 18/1633 | 1.1 (0.6–1.6) | 12/2406 | 0.5 (0.2–0.8) |
á…ŸBy timing of LPV/r initiation | ||||
ᅟᅟBefore conception | 2/333 | 0.6 (0.2–2.2) | 2/635 | 0.3 (0.1–1.1) |
ᅟᅟFirst trimester | 0/33 | – | 0/77 | – |
ᅟᅟSecond trimester | 8/858 | 0.9 (0.5–1.8) | 5/1397 | 0.4 (0.2–0.8) |
ᅟᅟThird trimester | 8/376 | 2.1 (1.1–4.1) | 5/264 | 1.9 (0.8–4.4) |
á…ŸBy baseline CD4+ T-cell count | ||||
ᅟᅟ<200 cells/mm3 | 3/157 | 1.9 (0.7–5.5) | 2/206 | 1.0 (0.3–3.5) |
ᅟᅟ200–349 cells/mm3 | 4/340 | 1.2 (0.5–3.0) | 1/506 | 0.2 (0.04–1.1) |
ᅟᅟ≥350 cells/mm3 | 4/600 | 0.7 (0.3–1.7) | 2/1171 | 0.2 (0.1–0.6) |
ᅟᅟMissing CD4+ T-cell count | 7/536 | 1.3 (0.6–2.7) | 7/523 | 1.3 (0.6–2.7) |