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Table 3 Outcomes of singleton pregnancies by NRTI backbone (n = 4762)

From: Maternal and foetal outcomes among 4118 women with HIV infection treated with lopinavir/ritonavir during pregnancy: analysis of population-based surveillance data from the national study of HIV in pregnancy and childhood in the United Kingdom and Ireland

 

ZDV + 3TC

FTC + TDF

ABC + 3TC

Other/Missing

P value

Preterm, n (%)

ᅟNo (≥37 wk)

2762 (87.0)

380 (86.2)

249 (88.6)

565 (84.0)

0.13

á…ŸYes (<37 wk)

412 (13.0)

61 (13.8)

32 (11.4)

108 (16.0)

Gestational age, n (%)

ᅟ≥37 wk

2762 (87.0)

380 (86.2)

249 (88.6)

565 (84.0)

0.31

ᅟ32–36 wk

317 (10.0)

49 (11.1)

24 (8.5)

88 (13.1)

á…Ÿ<32 wk

95 (3.0)

12 (2.7)

8 (2.9)

20 (3.0)

Low birth weight, n (%)

ᅟNo (≥2500 g)

2604 (85.0)

361 (85.1)

235 (86.1)

536 (84.5)

0.95

ᅟYes (<2500 g)

460 (15.0)

63 (14.9)

38 (13.9)

98 (15.5)

Low birth weight in term infants, n (%)

ᅟNo (≥2500 g)

2492 (93.1)

340 (92.6)

226 (93.0)

502 (93.0)

0.99

ᅟYes (<2500 g)

184 (6.9)

27 (7.4)

17 (7.0)

38 (7.0)

  1. Abbreviations: NRTI nucleoside reverse transcriptase inhibitor, ZDV zidovudine, 3TC lamivudine, FTC emtricitabine, TDF tenofovir, ABC abacavir