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Table 3 Outcomes of singleton pregnancies by NRTI backbone (n = 4762)

From: Maternal and foetal outcomes among 4118 women with HIV infection treated with lopinavir/ritonavir during pregnancy: analysis of population-based surveillance data from the national study of HIV in pregnancy and childhood in the United Kingdom and Ireland

  ZDV + 3TC FTC + TDF ABC + 3TC Other/Missing P value
Preterm, n (%)
ᅟNo (≥37 wk) 2762 (87.0) 380 (86.2) 249 (88.6) 565 (84.0) 0.13
ᅟYes (<37 wk) 412 (13.0) 61 (13.8) 32 (11.4) 108 (16.0)
Gestational age, n (%)
ᅟ≥37 wk 2762 (87.0) 380 (86.2) 249 (88.6) 565 (84.0) 0.31
ᅟ32–36 wk 317 (10.0) 49 (11.1) 24 (8.5) 88 (13.1)
ᅟ<32 wk 95 (3.0) 12 (2.7) 8 (2.9) 20 (3.0)
Low birth weight, n (%)
ᅟNo (≥2500 g) 2604 (85.0) 361 (85.1) 235 (86.1) 536 (84.5) 0.95
ᅟYes (<2500 g) 460 (15.0) 63 (14.9) 38 (13.9) 98 (15.5)
Low birth weight in term infants, n (%)
ᅟNo (≥2500 g) 2492 (93.1) 340 (92.6) 226 (93.0) 502 (93.0) 0.99
ᅟYes (<2500 g) 184 (6.9) 27 (7.4) 17 (7.0) 38 (7.0)
  1. Abbreviations: NRTI nucleoside reverse transcriptase inhibitor, ZDV zidovudine, 3TC lamivudine, FTC emtricitabine, TDF tenofovir, ABC abacavir