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Table 4 Initial ART regimens and risk of dropout

From: Predictors of dropout from care among HIV-infected patients initiating antiretroviral therapy at a public sector HIV treatment clinic in sub-Saharan Africa

 

Unadjusted analysis

Adjusted analysisb

Regimen backbonea

HR

P

AHR

P

AZT-based (reference)

-

-

-

-

TDF-based

1.2 (1.0–1.4)

0.022

1.4 (1.2–1.7)

<0.001

D4T-based‡

1.3 (0.98–1.6)

0.072

1.2 (0.92–1.5)

0.180

  1. aAZT-based regimens contain zidovudine (AZT), lamivudine (3TC), and either nevirapine (NVP) or efavirenz (EFV); TDF-based regimens contain tenofovir (TDF), 3TC or FTC, and either NVP or EFV; D4T-based regimens contain stavudine (D4T), 3TC, and either NVP or EFV
  2. bAdjusted for age, sex, year of ART initiation, and CD4+ T-cell count and hemoglobin concentration at ART initiation