From: Role of oral Minocycline in acute encephalitis syndrome in India – a randomized controlled trial
3 month mortality | Drug (N = 140) | Placebo (N = 141) | RR (95 % CI) for death with Drug | P* | ||
---|---|---|---|---|---|---|
N | % | N | % | |||
Dead | 43 | 30·7 | 52 | 36·9 | 0·83 (0·60-1·15) | 0·270 |
Alive | 92 | 65·7 | 84 | 59·5 | ||
untraced | 5 | 3·6 | 5 | 3·6 | ||
Age > 12 years (n = 100) | N = 50 | N = 50 | ||||
Dead | 15 | 30·0 | 21 | 42·0 | 0·70 (0·41-1·18) | 0·173 |
Alive | 32 | 64·0 | 25 | 50·0 | ||
untraced | 3 | 6·0 | 4 | 8·0 | ||
Age < =12 years | ||||||
(n = 181) | N = 90 | N = 91 | ||||
Dead | 28 | 31·1 | 31 | 34·1 | 0·92 (0·61-1·40) | 0·709 |
Alive | 60 | 66·6 | 59 | 63·7 | ||
untraced | 2 | 2·2 | 1 | 1·1 | ||
Considering that all those lost to follow up were dead at 3 months | ||||||
Dead | 48 | 34·3 | 57 | 40·4 | 0·85 (0·63-1·15) | 0·345 |
Alive | 92 | 65·7 | 84 | 59·6 | ||
Considering that all those lost to follow up were alive at 3 months | ||||||
Dead | 43 | 30·7 | 52 | 36·9 | 0·83 (0·60-1·16) | 0 · 274 |
Alive | 97 | 69·3 | 89 | 63·1 | ||
JE IgM positive patients (29) | ||||||
Dead (7) | 2 | 28.6 | 5 | 71.4 | 0.33 (0.03-2.72) | 0.384 |
Alive (20) | 11 | 55.0 | 9 | 45.0 | ||
untraced (2) | 2 | 28.6 | 0 | 0 |