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Table 1 Baseline comparison of drug and placebo groups

From: Role of oral Minocycline in acute encephalitis syndrome in India – a randomized controlled trial

Variable Drug (n = 140) Placebo (n = 141)
  N/ Mean % / SD N/ Mean % / SD
Mean Age1 15 · 4 15 · 7 16 · 1 17 · 6
Male sex2 102 72 · 8 108 76 · 6
Mean weight for age1 73 · 6 15 · 3 75 · 92 17 · 62
Mean duration of illness at presentation1 5 · 3 1 · 8 5 · 3 1 · 9
Headache2 66 47 · 1 62 43 · 9
Convulsion2 102 72 · 8 105 74 · 4
Mean GCS at admission1 8 · 6 2 · 6 8 · 2 2 · 5
Rash2 21 15.0 16 11.3
Swelling2 25 17.8 19 13.5
Bleeding2 5 3.5 13 9.2
Spleen palpable2 9 6.4 14 9.9
Meningeal signs2 63 45 · 0 58 41 · 1
Focal deficit2 11 7 · 8 17 12 · 0
↑ Tone2 65 46.4 67 47.5
↑ ICT2 13 9 · 3 20 14 · 2
Decerebration2 8 5 · 7 13 9.2
Mean Hb (gm/l) 1 105 20 106 24
Mean TLC1 (x 109/ l) 12.5 8.6 13.6 8.2
Mean polymorph %1 69 · 13 13 · 65 70 · 29 14 · 9
Mean platelets1(x 109/ l) 143 · 3 95 · 4 166 · 2 214 · 8
Mean CSF protein1 (g/l) 0 · 80 0 · 78 0 · 91 1 · 3
Mean CSF/ blood sugar ratio1 0 · 56 0. ·2 0 · 55 0 · 21
Mean CSF cells (per cu mm) 1 114 · 2 304 · 2 283 · 1 1118 · 7
Mean sAST1 (u/l) 116 · 6 149 · 5 132 · 8 244 · 2
Mean sALT1(u/l) 103 · 8 203 · 4 124 · 5 355 · 3
Mean s Protein (g/l) 1 74 68 77 79
Mean s Albumin (g/l) 1 34 07 32 07
Mean s Urea1 (mmol/l) 15 · 2 8 · 6 17 · 3 11 · 1
Mean s creatinine1 (μmol/l) 97 · 2 79 · 6 106 · 1 79 · 6
  1. 1 Comparison of means by 2 sample t test; 2 comparison of proportions by Chi square test; GCS: Glasgow Coma score; ICT: intracranial tension; Hb: hemoglobin; TLC: total leucocyte count; CSF: Cerebrospinal fluid; AST: aspartate transaminase; ALT: alanine transaminase; none of the differences are significant at p < 0 · 05