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Table 4 Analysis of the risk factors of radiological non-deterioration evaluated with chest X-ray and CT scans

From: Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease

Variables

Total

Non-deterioration

Worsening

Multivariate analysis

n

(n = 15)

(n = 18)

Odds ratio

Continuation of CAM or AZM

26

12 (80)

14 (78)

3.7 (0.28–50)

Treatment with 3 or more drugs

21

10 (67)

11 (66)

1.3 (0.16–11)

Age ≥75 years

8

3 (20)

5 (28)

 

Female

31

15 (100)

16 (89)

 

Nonsmoker

3

1 (6.7)

2 (11)

 

BMI 18 kg/m2

11

6 (40)

5 (28)

 

NB (radiological findings)

27

13 (87)

14 (78)

 

Total lesion extenta 1 or 2

26

13 (87)

13 (72)

 

Cavity

25

9 (60)

16 (89)

0.22 (0.018–2.7)

Albumin ≥3.5 g/dl

26

14 (93)

12 (67)

6.8 (0.28–168)

CRP <1.0 mg/dl*

16

12 (80)

4 (22)

12 (1.6–95)**

  1. Data are presented as no. (%)
  2. CAM clarithromycin, AZM azithromycin, NB nodular/bronchiectatic disease, BMI body mass index, CRP C-reactive protein
  3. *Significant at p < 0.005 in univariate analysis
  4. **Significant at p < 0.05 in multivariate analysis
  5. a1 within one third of unilateral lung field; 2 within unilateral lung field