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Table 4 Analysis of the risk factors of radiological non-deterioration evaluated with chest X-ray and CT scans

From: Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease

Variables Total Non-deterioration Worsening Multivariate analysis
n (n = 15) (n = 18) Odds ratio
Continuation of CAM or AZM 26 12 (80) 14 (78) 3.7 (0.28–50)
Treatment with 3 or more drugs 21 10 (67) 11 (66) 1.3 (0.16–11)
Age ≥75 years 8 3 (20) 5 (28)  
Female 31 15 (100) 16 (89)  
Nonsmoker 3 1 (6.7) 2 (11)  
BMI 18 kg/m2 11 6 (40) 5 (28)  
NB (radiological findings) 27 13 (87) 14 (78)  
Total lesion extenta 1 or 2 26 13 (87) 13 (72)  
Cavity 25 9 (60) 16 (89) 0.22 (0.018–2.7)
Albumin ≥3.5 g/dl 26 14 (93) 12 (67) 6.8 (0.28–168)
CRP <1.0 mg/dl* 16 12 (80) 4 (22) 12 (1.6–95)**
  1. Data are presented as no. (%)
  2. CAM clarithromycin, AZM azithromycin, NB nodular/bronchiectatic disease, BMI body mass index, CRP C-reactive protein
  3. *Significant at p < 0.005 in univariate analysis
  4. **Significant at p < 0.05 in multivariate analysis
  5. a1 within one third of unilateral lung field; 2 within unilateral lung field