Skip to main content

Advertisement

Table 3 Regimens after isolation of CAM-resistant MAC

From: Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease

Regimen   n Radiological findings: improved or unchanged at one year after treatment Sputum conversion by one year after treatment
CAM-containing regimen Total 24 11 8
Plus one drug RFP 1 1 1
  EB 1 0 0
Plus two drugs RFP + EB 5 2 3
  RFP + NQ 1 1 0
  EB + NQ 1 0 0
Plus three drugs RFP + EB + NQ 6 4 1
  RFP + EB + KM 3 1 2
  RFP + KM + NQ 2 1 0
  RFP + NQ + INH 1 0 1
  EB + KM + NQ 1 0 0
Plus four drugs RFP + EB + KM + NQ 1 0 0
  RFP + EB + KM + INH 1 1 0
AZM-containing regimen Total 2 1 2
Plus two drugs RFP + NQ 2 1 2
Regimen without CAM Total 7 3 2
Monotherapy EB 1 0 0
Three drugs RFP + EB + KM 1 0 0
  RFP + EB + NQ 5 3 2
  1. CAM clarithromycin, MAC Mycobacterium avium complex, RFP rifampicin, EB ethambutol, NQ new quinolone, KM kanamycin, INH isoniazid, AZM azithromycin