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Table 3 Regimens after isolation of CAM-resistant MAC

From: Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease

Regimen

 

n

Radiological findings: improved or unchanged at one year after treatment

Sputum conversion by one year after treatment

CAM-containing regimen

Total

24

11

8

Plus one drug

RFP

1

1

1

 

EB

1

0

0

Plus two drugs

RFP + EB

5

2

3

 

RFP + NQ

1

1

0

 

EB + NQ

1

0

0

Plus three drugs

RFP + EB + NQ

6

4

1

 

RFP + EB + KM

3

1

2

 

RFP + KM + NQ

2

1

0

 

RFP + NQ + INH

1

0

1

 

EB + KM + NQ

1

0

0

Plus four drugs

RFP + EB + KM + NQ

1

0

0

 

RFP + EB + KM + INH

1

1

0

AZM-containing regimen

Total

2

1

2

Plus two drugs

RFP + NQ

2

1

2

Regimen without CAM

Total

7

3

2

Monotherapy

EB

1

0

0

Three drugs

RFP + EB + KM

1

0

0

 

RFP + EB + NQ

5

3

2

  1. CAM clarithromycin, MAC Mycobacterium avium complex, RFP rifampicin, EB ethambutol, NQ new quinolone, KM kanamycin, INH isoniazid, AZM azithromycin