Lomentospora prolificans endocarditis - case report and literature review

BMC Infectious Diseases

Table 1 Cases of Lomentospora (Scedosporium) prolificans endocarditis 1990 – 2014

Case	Year	Age/Gender	Predisposition	Valve	Complications	Treatment/Surgery	Outcome
1⁽⁵⁾	1990	30 male	Intravenous drug user	Mitral	Septic arthritis	AmBisome	Survived
1⁽⁵⁾	1990	30 male	Intravenous drug user	Mitral	Septic arthritis	Flucytocine	Survived
2⁽⁵⁾	1997	67 female	Prosthetic aortic valve	Aortic	Cerebral emboli	AmBisome	Died
2⁽⁵⁾	1997	67 female	Prosthetic aortic valve	Aortic	Cerebral emboli	Fluconazole	Died
3⁽⁵⁾	2001	52 female	Multiple myeloma	Aortic	Endophthalmitis, intracranial haemorrhage	AmBisome	Died
						Itraconazole
						AVR
4⁽⁵⁾	2006	75 male	PPM	PPM	Pulmonary emboli	Voriconazole	Survived
4⁽⁵⁾	2006	75 male	PPM	PPM	Pulmonary emboli	PPM removal	Survived
5⁽⁹⁾	2010	50 male	Rheumatic disease	Mitral	Septic shock	AmBisome	Died
5⁽⁹⁾	2010	50 male	Rheumatic disease	Mitral	Septic shock	MVR	Died
6⁽⁵⁾	2010	29 female	ALL	Mitral	Endophthalmitis, osteomyelitis & cerebral emboli	AmBisome	Died
						Voriconazole
						MVR
7⁽¹⁰⁾	2013	35 male	Renal transplant	Aortic	Meningitis	AmBisome	Died
7⁽¹⁰⁾	2013	35 male	Renal transplant	Aortic	Meningitis	Voriconazole	Died
8⁽⁸⁾	2014	66 female	AML	Mitral	Sinusitis, pulmonary & splenic emboli	Voriconazole	Died
8⁽⁸⁾	2014	66 female	AML	Mitral	Sinusitis, pulmonary & splenic emboli	Terbinafine	Died
Case	2014	75 female	Ovarian cancer	Aortic	Cerebral emboli	Voriconazole	Died

ISSN: 1471-2334