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Table 2 Differential expression analysis of miR by qPCR in 163 clinical samples, in three independent phenotype comparisons

From: Inverse relationship between microRNA-155 and -184 expression with increasing conjunctival inflammation during ocular Chlamydia trachomatis infection

 

TF (n = 81) v N (n = 82)

TF Ct + (n = 47) V TF Ct- (n = 34)

TF Ct + (n = 47) V N Ct- (n = 77)

 

P value

Adj Pa

FCb

P value

Adj Pa

FCb

P value

Adj Pa

FCb

miR-184

5.69 x 10−8

7.96 x 10−7

0.30

0.7571

0.7571

0.88

3.06 x 10−7

1.07 x 10−6

0.28

miR-142-5p

6.46 x 10−7

4.52 x 10−6

1.82

1.63 x 10−5

7.58 x 10−5

2.53

2.3 x 10−12

3.22 x 10−11

2.83

miR-155-5p

1.56 x 10−5

7.29 x 10−5

1.73

9.45 x 10−6

6.62 x 10−5

2.50

1.18 x 10−9

5.51 x 10−9

2.58

miR-150-5p

0.0003

0.0011

1.56

1.41 x 10−6

1.98 x 10−5

3.24

8.56 x 10−10

5.51 x 10−9

2.71

miR-181b-5p

0.0010

0.0028

1.33

0.0018

0.005

1.74

1.58 x 10−6

4.44 x 10−6

1.70

miR-342-3p

0.0041

0.0096

1.12

0.0076

0.0178

1.50

0.0001

0.0002

1.34

miR-4728-3p

0.0103

0.0207

0.75

0.0353

0.0617

0.72

0.0005

0.0008

0.65

miR-181a-5p

0.0120

0.0211

1.30

0.0151

0.0301

1.40

0.0003

0.0006

1.54

miR-375

0.0871

0.1355

0.80

0.3054

0.3887

0.81

0.0615

0.0862

0.75

miR-132-3p

0.1628

0.2279

1.09

0.0009

0.0031

1.45

0.0023

0.0035

1.27

miR-10a-5p

0.2654

0.3378

1.16

0.6729

0.7247

0.92

0.3454

0.4030

1.15

miR-146b-3p

0.5491

0.6406

0.95

0.3666

0.4277

1.15

0.9425

0.9425

1.02

miR-147b

0.6203

0.6680

1.07

0.1073

0.1669

1.44

0.2394

0.3047

1.21

miR-1285

0.8683

0.8683

0.98

0.2095

0.2933

0.83

0.4434

0.4775

0.91

  1. Tests for difference were conducted with a T test or Wilcoxon signed rank test if data were not normally distributed
  2. N normal, TF follicular trachoma, Ct + Ct infected, Ct- no Ct infection detected
  3. aP adj = Adjusted P value
  4. bFC = Fold change
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BMC Infectious Diseases

ISSN: 1471-2334

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