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Table 2 Clinical features and outcome related gender in CM patients

From: Gender-specific contributing risk factors and outcome of female cryptococcal meningoencephalitis patients

 

Male (n = 77)

Female (n = 31)

P

Symptoms

 Headache, no. (%)

57 (74.0)

24 (77.4)

0.713

 Fever, no. (%)

48 (62.3)

19 (61.3)

0.919

 Seizure, no. (%)

5 (6.5)

3 (9.7)

0.687

 Dizziness, no. (%)

1 (1.3)

1 (3.2)

0.494

 Ataxia, no. (%)

3 (3.9)

1 (3.2)

1

 Unconsciousness, no. (%)

11 (14.3)

8 (25.8)

0.155

 Psychosis, no. (%)

2 (2.6)

2 (6.5)

0.577

CSF, mean ± SD

 Ratio of CSF glucose/Blood glucose, mean ± SD

0.30 ± 0.18

0.28 ± 0.18

0.54

 CSF pressure (mmH2O), mean ± SD

266.49 ± 60.13

271.94 ± 49.49

0.66

 CSF glucose (mmol/L), mean ± SD

2.08 ± 1.36

1.64 ± 1.01

0.80

 CSF protein (g/L), mean ± SD

0.94 ± 1.53

0.86 ± 0.51

0.11

Abnormal EEGa, no. (%)

17 (68.0)

10 (76.9)

0.71

Abnormal MRIb, no. (%)

25 (75.8)

9 (60.0)

0.31

Outcome

 Hospitalization length (days), mean ± SD

50.71 ± 55.36

53.35 ± 53.93

0.44

 Survival time (months), mean ± SD

30.40 ± 45.30

21.22 ± 36.15

0.09

 Dead, no. (%)

30 (45.5)

15 (53.6)

0.47

  1. aAbnormal EEG included 5 cases had normal background with focal slow wave and 5 had diffused slow wave in the background
  2. bAbnormal MRI included Bubble sign 5 cases (2 at the basal ganglion and 3 at subcortex), hydrocephalus 5 cases and 6 cases with abnormal cerebral lesions (6 cases with more than one abnormal features)