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Table 2 linear mixed-effects model results for association between KIR/HLA and HIV viraemia in 139 women with incident HIV infection followed up for up to 10 years post infection

From: Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women

  VL Intercept (log10/ml) Effect (log10/ml) SE nominal p-value
Fixed effects     
Haplotype     
AA 4.52 Ref 0.15 0.03
AB   −0.08 0.15  
BB   −0.44 0.18  
KIR loci     
KIR2DL2/KIR2DL2 4.08 Ref 0.15 0.02
KIR2DL2/KIR2DL3   0.33 0.16  
KIR2DL3/KIR2DL3   0.46 0.17  
KIR2DL5 4.43 −0.13 0.13 0.32
KIR3DL1/KIR3DL1 4.33 Ref 0.10 0.84
KIR3DL1/KIR3DS1   −0.05 0.24  
KIR3DS1/KIR3DS1 - - -  
KIR2DS1 4.36 −0.13 0.19 0.47
KIR2DS2 4.53 −0.28 0.13 0.03
KIR2DS3/KIR2DS3 4.03 Ref 0.19 0.14
KIR2DS3/KIR2DS5   0.01 0.25  
KIR2DS5/KIR2DS5   0.33 0.20  
KIR2DS4 4.43 −0.08 0.77 0.91
HLA groups     
Protective HLA-B alleles 4.38 −0.27 0.17 0.10
Harmful HLA-B alleles 4.26 0.25 0.13 0.06
Bw4 4.33 0.07 0.14 0.63
Bw6 4.39 −0.08 0.13 0.52
Number of C1 epitopes 4.40 −0.08 0.09 0.40
Number of C2 epitopes 4.25 0.07 0.09 0.43
Random Effects   Variance SD  
Weeks postinfection (Intercept) 0.02 0.12  
X002PID (Intercept) 0.61 0.78  
Residual   0.31 0.55