Cases (n = 44) | Controls (n = 371) | p | |
---|---|---|---|
Male sex, n (%) | 26 (59) | 186 (50) | 0.26 |
Age, years, mean (SD) | 14.9 (11.0) | 20.1 (13.2) | 0.01 |
Mutation CFTR ∆F508/∆F508, n (%) | 19 (43) | 150 (40) | 0.41 |
Bronchopulmonary bacterial colonization, n (%) | |||
S. aureus | 34 (77) | 234 (63) | 0.063 |
P. aeruginosa | 15 (34) | 195 (53) | 0.021 |
FEV1, %, mean (SD) | 79 (28) | 65 (25) | 0.005 |
FVC, %, mean (SD) | 87 (23) | 79 (21) | 0.073 |
Cystic fibrosis-specific FEV1, percentiles, mean (SD) | 52 (32) | 51 (30) | 0.78 |
Antibiotics, number of treatments, mean (SD) | |||
Oral | 2.2 (1.9) | 2.5 (1.9) | 0.17 |
Intravenous | 0.8 (1.5) | 1.1 (1.7) | 0.20 |
Oxygen therapy, n (%) | 2 (5) | 3(4) | 0.86 |
Noninvasive ventilation, n (%) | 1 (2) | 1(1) | 0.69 |