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Table 3 Comparison of laboratory data between patients with severe leptospirosis admitted to ICU and wards

From: Risk factors for intensive care unit admission in patients with severe leptospirosis: a comparative study according to patients’ severity

Parameters

ICU

Non-ICU

p

N = 83

N = 123

Creatinine (mg/dl)

3.97 ± 2.25

2.97 ± 2.4

0.004

Urea (mg/dl)

131.8 ± 68

101.2 ± 72.5

0.004

Potassium (mEq/L)

3.91 ± 0.85

3.9 ± 1.07

0.951

Sodium (mEq/L)

133 ± 6.61

130 ± 19

0.317

AST (UI/L)

169.8 ± 199

132.13 ± 183

0.285

ALT (UI/L)

101.83 ± 90

101.90 ± 153

0.998

LDH (UI/L)

810.25 ± 539

671.94 ± 420

0.416

Total bilirubin (mg/dl)

15 ± 12.2

8.6 ± 9.5

0.001

Direct bilirubin (mg/dl)

9.2 ± 8.5

5.9 ± 7.11

0.018

Indirect bilirubin (mg/dl)

4.48 ± 6.08

2.38 ± 3.22

0.013

Hematocrit (%)

29.6 ± 6.4

33.1 ± 8.63

0.003

Hemoglobin (g/dl)

10.2 ± 2.4

11.6 ± 1.95

<0.001

WBC (103/mm3)

14.30 ± 7.70

14.95 ± 1.82

0.772

Platelets (103/mm3)

94.42 ± 86.74

128.89 ± 137.01

0.035

pO2 (mmHg)

87.3 ± 32

83 ± 34

0.542

pCO2 (mmHg)

31.81 ± 9.4

32.64 ± 8.5

0.636

pH

7.35 ± 0.08

7.36 ± 0.07

0.127

Bicarbonate (mEq/L)

17.89 ± 4.82

18.8 ± 4.89

0.330

SaO2 (%)

93.82 ± 5.7

91.6 ± 10.17

0.190

  1. AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, WBC white blood cells, PO 2 O2 partial pressure, PCO 2 PCO2 partial pressure, SaO 2 O2 saturation
  2. Chi-squared test, T-Student test and Mann–Whitney test were used to perform this comparison. Values expressed as mean ± SD and percentage. P values ≤ 0.05 were considered statistically significant