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Table 3 Comparison of laboratory data between patients with severe leptospirosis admitted to ICU and wards

From: Risk factors for intensive care unit admission in patients with severe leptospirosis: a comparative study according to patients’ severity

Parameters ICU Non-ICU p
N = 83 N = 123
Creatinine (mg/dl) 3.97 ± 2.25 2.97 ± 2.4 0.004
Urea (mg/dl) 131.8 ± 68 101.2 ± 72.5 0.004
Potassium (mEq/L) 3.91 ± 0.85 3.9 ± 1.07 0.951
Sodium (mEq/L) 133 ± 6.61 130 ± 19 0.317
AST (UI/L) 169.8 ± 199 132.13 ± 183 0.285
ALT (UI/L) 101.83 ± 90 101.90 ± 153 0.998
LDH (UI/L) 810.25 ± 539 671.94 ± 420 0.416
Total bilirubin (mg/dl) 15 ± 12.2 8.6 ± 9.5 0.001
Direct bilirubin (mg/dl) 9.2 ± 8.5 5.9 ± 7.11 0.018
Indirect bilirubin (mg/dl) 4.48 ± 6.08 2.38 ± 3.22 0.013
Hematocrit (%) 29.6 ± 6.4 33.1 ± 8.63 0.003
Hemoglobin (g/dl) 10.2 ± 2.4 11.6 ± 1.95 <0.001
WBC (103/mm3) 14.30 ± 7.70 14.95 ± 1.82 0.772
Platelets (103/mm3) 94.42 ± 86.74 128.89 ± 137.01 0.035
pO2 (mmHg) 87.3 ± 32 83 ± 34 0.542
pCO2 (mmHg) 31.81 ± 9.4 32.64 ± 8.5 0.636
pH 7.35 ± 0.08 7.36 ± 0.07 0.127
Bicarbonate (mEq/L) 17.89 ± 4.82 18.8 ± 4.89 0.330
SaO2 (%) 93.82 ± 5.7 91.6 ± 10.17 0.190
  1. AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, WBC white blood cells, PO 2 O2 partial pressure, PCO 2 PCO2 partial pressure, SaO 2 O2 saturation
  2. Chi-squared test, T-Student test and Mann–Whitney test were used to perform this comparison. Values expressed as mean ± SD and percentage. P values ≤ 0.05 were considered statistically significant