Fig. 2

Epithelial cell-specific (ARPE-19) plaque reduction neutralisation capacity of the sera 1–4. Reference sera include a negative pool (N = 100 sera from seronegative women at birth), and a pool of latently CMV-infected women at birth (IgG positive, IgM negative, high IgG avidity) as well as the hyperimmunoglobulin preparation Cytotect (Biotest, Germany) [11]. The shaded columns show the mean number (N = 3 replica) of CMV IE1-stained plaques (N_IEA plaques) in the absence of CMV-specific antibodies after 5 days of incubation. Black columns show the percentage of neutralisation via plaque reduction of each serum panel. Gray columns show CMV IgG avidity (AI ECLIA, %). Specific NT capacity is not present in early sera of the patient (within one week of admission). However, after 5 weeks, NT₅₀ values are reached