Table 4 Carriage of specific pneumococcal subtypes in children with asthma, by pneumococcal vaccination status
Vaccinated with PCV7, n (%) | Not vaccinated with PCV7, n (%) | Crude OR (95 % CI) | OR (95 % CI)a | |
|---|---|---|---|---|
Total carriers | 93 | 99 | ||
Carriers of serotypes not included in PCV13 | 4 (4.3) | 6 (6.0) | 0.84 (0.23–3.07) | 0.97 (0.25–3.77) |
Carriers of PCV13 serotypes | ||||
1 | 32 (34.4) | 29 (29.2) | 1.40 (0.80–2.47) | 1.23 (0.69–2.21) |
2 | 41 (44.1) | 28 (28.2) | 1.86 (1.08–3.21) | 1.64 (0.93–2.89) |
≥3 | 16 (17.2) | 36 (36.6) | 0.57 (0.30–1.08) | 0.46 (0.23–0.91) |
Carriers of different PCV13 serotypes | ||||
Serotype 1 | 1 (1.0) | 2 (2.0) | 0.58 (0.05–6.47) | 0.56 (0.05–6.40) |
Serotype 3 | 12 (13.0) | 11 (11.1) | 1.29 (0.56–3.00) | 1.18 (0.50–2.80) |
Serotype 4 | 26 (28.0) | 39 (39.4) | 0.75 (0.43–1.28) | 0.62 (0.36–1.09) |
Serotype 5 | 15 (16.1) | 23 (23.2) | 0.74 (0.38–1.47) | 0.68 (0.33–1.38) |
Serotype 6A | 5 (5.4) | 6 (6.1) | 0.97 (0.29–3.24) | 0.65 (0.18–2.40) |
Serotype 6B | 0 (0.0) | 3 (3.0) | NE | NE |
Serotype 7 F | 2 (2.1) | 4(4.0) | 0.58 (0.10–3.20) | 0.60 (0.10–3.49) |
Serotype 9 V | 18 (19.3) | 22 (22.1) | 0.95 (0.49–1.83) | 0.95 (0.48–1.87) |
Serotype 14 | 0 (0.0) | 1 (1.0) | NE | NE |
Serotype 18C | 0 (0.0) | 0 (0.0) | NE | NE |
Serotype 19A | 3 (3.2) | 7 (7.1) | 0.49 (0.13–1.94) | 0.43 (0.11–1.77) |
Serotype 19 F | 83 (89.2) | 84 (84.9) | 1.27 (0.86–1.88) | 1.13 (0.75–1.70) |
Serotype 23 F | 2 (2.1) | 2 (2.0) | 1.17 (0.16–8.40) | 0.83 (0.11–6.26) |