High Streptococcus pneumoniae colonization prevalence among HIV-infected Kenyan parents in the year before pneumococcal conjugate vaccine introduction

Table 2 Pneumococcal colonization among parents of children <5 years of age living in the same compound in Western Kenya, by HIV-status (N = 973)

	HIV- Infected only	HIV-uninfected only	HIV-unknown only	All Participants
	N (%)	N (%)	N (%)	N (%)
Number of participants	549	153	271	973
Pneumococcal colonization, any type^a	237 (43.2)	41 (26.8)	97 (35.8)	375 (38.5)
PCV10 type only	71 (12.9)	18 (11.8)	26 (9.6)	115 (11.8)
PCV13-type only	108 (19.7)	24 (15.7)	44 (16.2)	176 (18.1)
Total number of isolates detected^b	242	41	98	381
Number of different pneumococcal serotypes detected per person^c,a
0	312 (56.8)	112 (73.2)	174 (64.2)	598 (61.4)
1	232 (42.3)	41 (26.8)	96 (35.4)	369 (38.0)
2	5 (0.9)	0	1 (0.4)	6 (0.6)
Total number of different pneumococcal serotypes detected^e	35	16	30	41
Serotype diversity index^d,e	0.14	0.39	0.31	0.11

^ap-value comparing HIV-infected compared to HIV-uninfected <0.001
^bAny pneumococcal colony suspected of being alpha-hemolytic was selected for identification by susceptibility to optochin and bile solubility. In some cases, more than one colony was identified per plate
^cNo participant had >2 serotypes identified
^dSerotype diversity index = total number of different pneumococcal serotypes detected divided by total number of isolates detected; Maximum diversity is 1.0 and least diversity is 0
^eDoes not include non-typeable isolates: HIV-infected (1), HIV-uninfected (2), HIV-unknown (3)

ISSN: 1471-2334