BMC Infectious Diseases

Table 2 Correlation between cytokine transcript levels in PBMC and liver biopsy grading scores and ALT activity in 22 patients with chronic hepatitis C prior to the initiation of antiviral therapy

From: The correlation between pretreatment cytokine expression patterns in peripheral blood mononuclear cells with chronic hepatitis c outcome

Cytokine^a	Liver histology Grading		ALT activity in serum
Cytokine^a	Spearman r	Statistical significance	Spearman r	Statistical significance
IL–1α	0.34	NS	0.62	0.025
IL–4	0.31	NS	0.66	0.002^b
IL–6	0.47	0.05	0.46	0.050
IL–10	0.18	NS	0.59	0.005^b
IL–12	0.27	NS	0.49	0.028
IL–15	0.19	NS	0.64	0.007^b
GM–CSF	0.43	NS	0.49	0.030
M–CSF	0.67	0.010	0.56	0.040
MCP–2	0.28	NS	0.54	0.009^b
TGF–β	0.39	NS	0.59	0.004^b

^aOnly cytokines with p≤ 0.05 are listed
^bstatistically significant (p≤ 0.05) using Benjamini–Hochberg procedure to correct for multiple testing [24]

Back to article page

ISSN: 1471-2334

Contact us

Submission enquiries: bmcinfectiousdiseases@biomedcentral.com
General enquiries: ORSupport@springernature.com