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Table 1 Some clinical, virological and biochemical characteristics of the 22 studied patients

From: The correlation between pretreatment cytokine expression patterns in peripheral blood mononuclear cells with chronic hepatitis c outcome

Parameter

SVR patients (n = 12)

Non-responders (n = 10)

Statistical significance

Gender (M/F)

6/6

6/4

NS

Age (yr)a

46.3 ± 18.7

46.8 ± 12.8

NS

Baseline viral load (IU/ml)

1.33 × 106 ± 1.28 × 106

1.04 × 106 ± 1.14 × 106

NS

Serum ALT activity (U/L)

94.1 ± 79.9

96.4 ± 50.3

NS

Grading

2.42 ± 0.16

1.92 ± 0.17

P = 0.029

Staging

2.54 ± 0.23

1.88 ± 0.14

P = 0.053

IL28B genotype

CC

7

0

P = 0.005

CT

3

7

TT

2

3

Genotype

1b

7

8

NS

3a

4

1

4

1

1

Complianceb

8 (66 %)

7 (70 %)

 

Leukocytes (109/L)

5.95 ± 2.22

5.80 ± 1.95

 

Neutrophils (109/L)

3.28 ± 1.51

3.11 ± 1.32

 
  1. NS not significant
  2. aAll values are means ± SD
  3. b According to the “80/80/80” rule [25]