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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: The correlation between pretreatment cytokine expression patterns in peripheral blood mononuclear cells with chronic hepatitis c outcome

Fig. 1

Real-time PCR analysis of gene transcripts in peripheral blood mononuclear cells (PBMC) from HCV-infected patients prior to antiviral treatment. Relative quantification of gene expression was calculated using the 2−∆ΔCT method, and all data were normalized to histone 3 RNA. Solid circles represent patients achieving sustained virological response (SVR), and open circles represent patients who failed treatment. Horizontal lines indicate median values. Missing data represent situation in which the mRNA was below the detection limit. IL, Interleukin; TNF, Tumor necrosis factor; HLA-DR, human leukocyte antigen DR1; IFN, Interferon; IP-10, IFN-inducible protein-10; GM-CSF, Granulocyte-macrophage colony-stimulating factor; M-CSF, Macrophage colony-stimulating factor; MCP, Monocyte chemotactic protein; MIP, Macrophage inflammatory protein; RANTES, Regulated on activation normal T cell expressed and secreted; TGF, Transforming growth factor; MxA, Myxovirus resistance protein. *, statistically significant (p ≤ 0.05) by Mann-Whitney U test only; **. statistically significant (p ≤ 0.05) using Benjamini–Hochberg procedure to correct for multiple testing [24]

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