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Table 6 Vaccination options for the current UK childhood immunisation programme and plausible extensions to it in the foreseeable future

From: A novel approach to evaluating the UK childhood immunisation schedule: estimating the effective coverage vector across the entire vaccine programme

Diseases targeted Option number Vaccine products Number of visits
Current programme: Diphtheria, Pertussis, Tetanus, Polio, Neisseria Men C, Hib, Pneumococcal disease, Measles, Mumps, Rubella and Rotavirus Option 1 Pediacel; Repevax (or Infanrix IPV); NeisVac (or Menjugate Kit); Menitorix; Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix 5
Option 2 Pediacel; NeisVac (or Menjugate Kit); Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix 5
As in current programme + Hepatitis B Option 3 Pediacel; Repevax (or Infanrix IPV); NeisVac (or Menjugate Kit); Menitorix; Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix; HBVaxPro 6
Option 4 Pediacel; NeisVac (or Menjugate Kit); Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix; HBVaxPro 6
Option 5 Infanrix Hexa; NeisVac (or Menjugate Kit); Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix 5
As in current programme + Men B Option 6 Pediacel; Repevax (or Infanrix IPV); NeisVac (or Menjugate Kit); Menitorix; Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix; Bexsero 5
Option 7 Pediacel; NeisVac (or Menjugate Kit); Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix; Bexsero 5
As in current programme + Hepatitis B + Men B Option 8 Infanrix Hexa; NeisVac (or Menjugate Kit); Prevenar 13; MMR-VAXPRO (or Priorix); Rotarix; Bexsero 5
  1. Four scenarios were considered: the current immunisation programme; adding Hepatitis B vaccination to the current programme; adding Meningitis B vaccination to the current programme; and adding both Hepatitis B and Meningitis B vaccination to the current programme. For each scenario we present the feasible combinations of vaccine products that could target the vaccine preventable diseases, each of which represents a plausible schedule option. Overall this gives rise to the eight possible options listed: the vaccination schedules for each of these options are contained in Additional file 1