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Table 1 Susceptibility of four PPNG isolates producing TEM-220 β-lactamase and PPNG strains containing the T539C substitution in the bla TEM allele

From: Prevalence of bla TEM-220 gene in Penicillinase-producing Neisseria gonorrhoeae strains carrying Toronto/Rio plasmid in Argentina, 2002 – 2011

 

MIC (μg/ml)

Antimicrobial agent

aT539C

TEM-220

 
 

bMIC50

cMIC90

Isolate 1

Isolate 2

Isolate 3

Isolate 4

Penicillin

64

128

32

64

32

64

Ampicillin

128

256

64

128

128

128

Cefuroxime

0,25

0,5

0,125

0,125

0,125

0,125

Cefixime

0,016

0,016

0,008

0,008

0,008

0,008

Ceftriaxone

0,004

0,008

0,008

0,004

0,008

0,004

Tetracycline

1

4

0,5

1

1

1

Ciprofloxacin

0,004

0,008

0,002

0,004

0,004

0,004

Azithromycin

0,25

0,25

0,25

0,25

0,25

0,25

  1. aNumber of PPNG isolates containing the T539C substitution (n = 137)
  2. bMIC50 : MIC of inhibition of 50 % of strains
  3. cMIC90: MIC of inhibition of 90 % of strains