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Table 4 Diagnoses/complications of PCR-confirmed influenza patients in Bavarian PICUs, 2010–2013. Data are shown by virus type/subtype (n = 47)a

From: Continued high incidence of children with severe influenza A(H1N1)pdm09 admitted to paediatric intensive care units in Germany during the first three post-pandemic influenza seasons, 2010/11–2012/13

  Influenza type/subtype Comparison of seasons
A(H1N1)pdm09b
Complications All patients A A(H1N1)pdm09 A(H3N2) A (subtype n.a.) B S1 vs S3
N = 47 N = 40 N = 32 N = 4 N = 4 N = 7 p-value*
At least 1 specific complication; n (%) 42 (89.4) 36 (90.0) 29 (90.6) 3 (75.0) 4 (100.0) 6 (85.7) 0.497
Influenza-associated pneumonia; n (%) 29 (61.7) 26 (65.0) 22 (68.8) 1 (25.0) 3 (75.0) 3 (42.9) 1.000
Bronchitis/bronchiolitis; n (%) 15 (31.9) 13 (32.5) 8 (25.0) 3 (75.0) 2 (50.0) 2 (28.6) 0.004
Secondary bacterial pneumonia; n (%) 12 (25.5) 10 (25.0) 10 (31.3) 0 (0.0) 0 (0.0) 2 (28.6) 0.452
ARDS; n (%) 10 (21.3) 9 (22.5) 7 (21.9) 2 (50.0) 0 (0.0) 1 (14.3) 0.099
Sepsis; n (%) 6 (12.8) 6 (15.0) 4 (12.5) 1 (25.0) 1 (25.0) 0 (0.0) 1.000
Febrile convulsions; n (%) 3 (6.4) 2 (5.0) 2 (6.3) 0 (0.0) 0 (0.0) 1 (14.3) 1.000
Encephalitis/encephalopathy; n (%) 1 (2.1) 1 (2.5) 1 (3.1) 0 (0.0) 0 (0.0) 0 (0.0) 1.000
Laryngitis/pseudocroup; n (%) 1 (2.1) 1 (2.5) 1 (3.1) 0 (0.0) 0 (0.0) 0 (0.0) 1.000
Otherc; n (%) 6 (12.8) 5 (12.5) 5 (15.6) 0 (0.0) 0 (0.0) 1 (14.3) 1.000
  1. n.a. not available, vs versus
  2. *Fisher’s Exact test
  3. aClinical data was not available for one influenza A(H1N1)pdm09 and three influenza B patients
  4. bComparison restricted to influenza A(H1N1)pdm09 patients from Season 1 (S1; Oct10–Sep 11; n = 18) and Season 3 (S3; Oct12–Sep 13; n = 13)
  5. cOther complications, excluding the pre-defined complications otitis media, status asthmaticus, and myocarditis (for these pre-defined complications, no case was reported)