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Table 2 Demographic characteristics and details on PICU/hospital admission of PCR-confirmed influenza patients in Bavarian PICUs, 2010–2013. Data are shown by virus type/subtype (n = 47)a

From: Continued high incidence of children with severe influenza A(H1N1)pdm09 admitted to paediatric intensive care units in Germany during the first three post-pandemic influenza seasons, 2010/11–2012/13

  Influenza type/subtype Comparison of seasons
A(H1N1)pdm09c
Characteristics All patients A A(H1N1)pdm09 A(H3N2) A (subtype n.a.) B S1 vs S3
N = 47 N = 40 N = 32 N = 4 N = 4 N = 7 p-value*
Male sex; n (%) 28 (59.6) 24 (60.0) 18 (56.3) 3 (75.0) 3 (75.0) 4 (57.1) 0.481
Age at ICU admission, in years (median, IQR) 4.8 (1.6–11.0) 4.7 (1.1–11.1) 5.4 (1.6–11.3) 0.9 (0.6–4.4) 4.9 (2.3–10.4) 5.0 (2.3–9.4) 0.020
Interval between onset of ARI symptoms and ICU admission, in days (median, IQR)b 3.0 (2.0–5.3) 3.0 (1.0–6.0) 3.5 (1.0–5.8) 2.5 (2.0–10.5) 3.0 (n.a.) 3.0 (1.5–5.0) 0.041
Interval between onset of ARI symptoms and hospital admission, in days (median, IQR)b 3.0 (1.0–5.0) 3.0 (1.0–5.0) 3.0 (1.0–5.0) 2.5 (2.0–4.5) 2.0 (n.a.) 3.0 (1.5–4.0) 0.217
Duration of ICU stay, in days (median, IQR) 3.0 (1.0–11.0) 3.5 (2.0–12.5) 3.0 (1.3–12.3) 9.5 (7.3–29.0) 6.5 (2.0–16.3) 1.0 (1.0–11.0) 0.837
Duration of hospital stay, in days (median, IQR) 7.5 (4.0–16.3) 8.0 (4.0–16.0) 7.0 (4.0–16.0) 11.0 (8.8–59.0) 13.0 (7.3–20.3) 5.0 (3.0–22.0) 0.953
  1. n.a. not available, vs versus
  2. *Fisher’s Exact Test or Mann–Whitney U-test, respectively
  3. aClinical data was not available for one influenza A(H1N1)pdm09 and three influenza B patients
  4. bDate of ARI symptom onset missing for nine patients
  5. cComparison restricted to influenza A(H1N1)pdm09 patients from Season 1 (S1; Oct10–Sep 11; n = 18) and Season 3 (S3; Oct12–Sep 13; n = 13)