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Table 3 Multivariate models for the prediction of hepatic decompensation and/or HCC

From: Progression of liver stiffness predicts clinical events in HIV/HCV-coinfected patients with compensated cirrhosis

 

Parameter

Multivariate hazard ratio (95 % CI)

P multivariate

Model 1

   
 

Age (years)a

1.11 (1.01–1.16)

0.028

 

Female sex

3.2 (0.59–17.16)

0.177

 

SVRb during follow-up

0.46 (0.12–1.81)

0.266

 

Platelet count (/mm3) ≥ 150.000

4.01 (0.81–19.85)

0.089

 

Child-Turcotte-Pugh class A

1.49 (0.18–12.41)

0.713

 

Baseline liver stiffness ≥ 21 kPa

1.9 (0.59–6.07)

0.279

Model 2

   
 

Age (years)a

1.06 (0.99–1.13)

0.053

 

Female sex

2.36 (0.46–12.09)

0.302

 

SVRb during follow-up

0.26 (0.06–1.14)

0.075

 

Platelet count (/mm3) ≥ 150.000

2.99 (0.61–14.77)

0.178

 

Child-Turcotte-Pugh class A

1.88 (0.23–15.55)

0.556

 

Progression of liver stiffness ≥ 30 % from baseline

4.63 (1.34–16.02)

0.015

  1. aConsidered as a continuous variable for multivariate analyses
  2. bSVR: Sustained virological response. Model 1 indicates the multivariate model based on baseline liver stiffness. Model 2 indicates the multivariate model based on the progression of liver stiffness