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Table 3 Multivariate models for the prediction of hepatic decompensation and/or HCC

From: Progression of liver stiffness predicts clinical events in HIV/HCV-coinfected patients with compensated cirrhosis

  Parameter Multivariate hazard ratio (95 % CI) P multivariate
Model 1    
  Age (years)a 1.11 (1.01–1.16) 0.028
  Female sex 3.2 (0.59–17.16) 0.177
  SVRb during follow-up 0.46 (0.12–1.81) 0.266
  Platelet count (/mm3) ≥ 150.000 4.01 (0.81–19.85) 0.089
  Child-Turcotte-Pugh class A 1.49 (0.18–12.41) 0.713
  Baseline liver stiffness ≥ 21 kPa 1.9 (0.59–6.07) 0.279
Model 2    
  Age (years)a 1.06 (0.99–1.13) 0.053
  Female sex 2.36 (0.46–12.09) 0.302
  SVRb during follow-up 0.26 (0.06–1.14) 0.075
  Platelet count (/mm3) ≥ 150.000 2.99 (0.61–14.77) 0.178
  Child-Turcotte-Pugh class A 1.88 (0.23–15.55) 0.556
  Progression of liver stiffness ≥ 30 % from baseline 4.63 (1.34–16.02) 0.015
  1. aConsidered as a continuous variable for multivariate analyses
  2. bSVR: Sustained virological response. Model 1 indicates the multivariate model based on baseline liver stiffness. Model 2 indicates the multivariate model based on the progression of liver stiffness