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Table 2 Univariate associations between emergence of and episode of hepatic decompensation and/or HCC and other parameters (n = 275)

From: Progression of liver stiffness predicts clinical events in HIV/HCV-coinfected patients with compensated cirrhosis

Parameter Category No. (%) with decompensation P Bivariate (Log rank test)
Sex Male 16 (6)  
Female 3 (10) 0.4
Age < 44 years 6 (5)  
≥ 44 years 13 (8) 0.2
Hepatitis B virus surface antigen Negative 17 (6)  
Positive 2 (25) 0.15
HCV genotype 1–4 13 (6)  
2–3 6 (9) 0.4
HCV RNA load (log10 IU/mL)a < 6.7 13 (7)  
≥ 6.7 5 (8) 0.5
Therapy against HCV during follow-up No therapy or therapy without SVRb 16 (6)  
SVRb 3 (11) 0.6
CD4 cell count (cells/mm3) < 200 5 (8)  
≥ 200 14 (6) 0.5
Platelet count (/mm3) < 150.000 16 (9)  
≥ 150.000 3 (3) 0.061
APRIc score < 1.5 9 (7)  
≥ 1.5 10 (7) 0.9
Child-Turcotte-Pugh class A 15 (6)  
B 4 (15) 0.002
MELDd scoree < 14 17 (7)  
≥ 14 0 (0) 0.6
Liver stiffness (kPa) < 21 7 (5)  
≥ 21 12 (9) 0.18
Progression of liver stiffness ≥ 30 % from baselinef No 5 (3)  
Yes 10 (13) 0.011
  1. aAvailable in 254 patients
  2. bSVR: Sustained virological response
  3. cAPRI: AST platelet ratio index
  4. dModel for end-stage liver disease
  5. eAvailable in 251 patients
  6. fEvaluable in 247 patients