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Table 6 Association of IL-23R polymorphisms and pulmonary infiltration and cavitary formation in pulmonary TB patients

From: The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs

dbSNP ID/ Genotype Cavitary formation (N = 250) OR (95 % CI) Pulmonary infiltration (N = 250) OR (95 % CI)
   No Cavity lesion Cavity lesion   ≤ 1/3 of one lung >1/3 of one lung  
   N = 179 n (%) N = 71 n (%)   N = 138 n (%) N = 112 n (%)  
rs1884444 TT 88 (49.2) 15 (21.1) 1 58 (42.0) 45 (40.2) 1
  GG + GT 91 (50.8) 56 (78.9) 3.61 (1.90–6.85) 80 (58.0) 67 (59.8) 1.08 (0.65–1.79)
rs10889664 CC 87 (48.6) 36 (50.7) 1 68 (49.3) 55 (49.1) 1
  TT + CT 92 (51.4) 35 (49.3) 0.92 (0.53–1.59) 70 (50.7) 57 (50.9) 1.01 (0.61–1.66)
rs11465788 TT 74 (41.3) 31 (43.7) 1 57 (41.3) 48 (42.9) 1
  CC + CT 105 (58.7) 40 (56.3) 0.91 (0.52–1.59) 81 (58.7) 64 (57.1) 0.94 (0.57–1.55)
rs7518660 GG 7 (4.1) 5 (7.0) 1 7 (5.1) 5 (4.5) 1
  AA + AG 172 (95.9) 66 (93.0) 0.54 (0.17–1.75) 131 (94.9) 107 (95.5) 1.14 (0.35–3.71)
rs11465802 CC 72 (40.2) 30 (42.3) 1 56 (40.6) 46 (41.1) 1
  AA + AC 107 (59.8) 41 (57.7) 0.92 (0.53–1.61) 82 (59.4) 66 (58.9) 0.98 (0.59–1.63)
rs10889677 AA 39 (21.8) 14 (19.7) 1 31 (22.5) 22 (19.6) 1
  CC + AC 140 (78.2) 57 (80.3) 1.13 (0.57–2.25) 107 (77.5) 90 (80.4) 1.19 (0.64–2.19)
CNV CN = 2 144 (80.4) 56 (78.9) 1 109 (79.0) 91 (81.3) 1
  CN = 1, 3, 4 35 (19.6) 15 (21.1) 1.10 (0.56–2.17) 29 (21.0) 21 (18.7) 0.87 (0.46–1.62)
  1. OR odds ratio, CI confidence interval