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Table 3 Association of IL-23R SNPs genotypes with pulmonary TB under different genotype models

From: The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs

dbSNP ID

Allele

Genetic Model

OR (95 % CI)

ORc (95 % CI)

ORa (95 % CI)

rs1884444

T > G

Dominant

1.08 (0.75–1.56)

1.12 (0.83–1.77)

1.22 (0.89–1.83)

  

Recessive

1.17 (0.72–1.79)

1.21 (0.77–1.84)

1.33 (0.79–1.94)

  

Additive

0.86 (0.61–1.23)

0.91 (0.81–1.34)

0.93 (0.85–1.46)

rs10889664

C > T

Dominant

1.16 (0.81–1.67)

1.22 (0.90–1.83)

1.31 (0.94–1.92)

  

Recessive

0.86 (0.62–1.65)

0.89 (0.72–1.88)

0.95 (0.76–1.97)

  

Additive

1.16 (0.81–1.64)

1.34 (0.93–1.77)

1.54 (0.95–1.83)

rs11465788

T > C

Dominant

0.99 (0.68–1.43)

1.02 (0.74–1.65)

1.23 (0.82–1.75)

  

Recessive

1.22 (0.77–1.30)

1.24 (0.82–1.43)

1.37 (0.85–1.55)

  

Additive

0.88 (0.62–1.25)

0.93 (0.81–1.38)

0.95 (0.86–1.43)

rs7518660

G > A

Dominant

4.83 (3.10–7.53)

4.91 (3.25–8.17)

4.78 (3.14–8.52)

  

Recessive

6.25 (3.85–10.00)

6.54 (3.62–10.34)

6.38 (3.51–10.46)

  

Additive

0.88 (0.62–1.25)

0.91 (0.58–1.36)

0.93 (0.65–1.47)

rs11465802

C > A

Dominant

0.91 (0.62–1.33)

0.95 (0.57–1.46)

1.01 (0.48–1.52)

  

Recessive

1.16 (0.60–1.75)

1.23 (0.54–1.86)

1.45 (0.76–1.92)

  

Additive

1.02 (0.72–1.46)

1.14 (0.65–1.57)

1.26 (0.63–172))

rs10889677

A > C

Dominant

0.66 (0.44–0.99)

0.72 (0.39–1.12)

0.88 (0.42–1.23)

  

Recessive

1.53 (1.01–2.31)

1.61 (0.99–1.98)

1.75 (1.05–2.03)

  

Additive

1.01 (0.71–1.43)

1.15 (0.68–1.74)

1.24 (0.73–1.82)

  1. OR odds ratio, CI confidence interval
  2. OR for comparison of genetic models by conditioned logistic regression analysis
  3. ORc = OR value after Bonferroni correction
  4. ORa = OR value adjusted for BMI