Skip to main content

Table 2 Genotype and allele frequencies distribution of IL-23R polymorphisms between controls and cases

From: The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs

dbSNP ID/CNV Genotype/Allele Controls n (%) PTB cases n (%) OR (95 % CI)
rs1884444 TT 82 (33.1) 87 (34.8) 1
  GT 122 (49.2) 114 (45.6) 0.88 (0.59–1.31)
  GG 44 (17.7) 49 (19.6) 1.05 (0.63–1.74)
  T 286 (57.7) 288 (57.6) 1
  G 210 (42.3) 212 (42.4) 1.00 (0.78–1.29)
rs10889664 CC 93 (37.5) 103 (41.2) 1
  CT 117 (47.2) 109 (43.6) 0.84 (0.57–1.23)
  TT 38 (15.3) 38 (15.2) 0.90 (0.53–1.53)
  C 303 (61.1) 315 (63.0) 1
  T 193 (38.9) 185 (37.0) 0.92 (0.71–1.19)
rs11465788 TT 85 (34.7) 87 (34.9) 1
  CT 120 (49.0) 114 (45.8) 0.93 (0.63–1.38)
  CC 40 (16.3) 48 (19.3) 1.17 (0.70–1.96)
  T 290 (59.2) 288 (57.8) 1
  C 200 (40.8) 210 (42.2) 1.06 (0.82–1.36)
rs7518660 GG 105 (42.3) 33 (13.2) 1
  AG 116 (46.8) 109 (43.6) 2.99 (1.87–4.79)
  AA 27 (10.9) 108 (43.2) 12.73 (7.16–22.6)
  G 326 (65.7) 175 (35.0) 1
  A 170 (34.3) 325 (65.0) 3.56 (2.74–4.62)
rs11465802 CC 74 (30.0) 70 (28.0) 1
  AC 121 (49.0) 121 (48.4) 1.06 (0.70–1.60)
  AA 52 (21.0) 59 (23.6) 1.20 (0.73–1.97)
  C 269 (54.5) 261 (52.2) 1
  A 225 (45.5) 239 (47.8) 1.10 (0.85–1.41)
rs10889677 AA 76 (30.9) 57 (22.9) 1
  AC 119 (48.4) 121 (48.6) 1.36 (0.89–2.08)
  CC 51 (20.7) 71 (28.5) 1.85 (1.13–3.05)
  A 271 (55.1) 235 (47.2) 1
  C 221 (44.9) 263 (52.8) 1.37 (1.07–1.76)
CNV CN < 2 3 (1.2) 7 (2.8) 2.66 (0.68–10.41)
  CN = 2 230 (92.0) 202 (80.8) 1
  CN > 2 17 (6.8) 41 (16.4) 2.75 (1.51–4.98)
  1. PTB pulmonary tuberculosis, OR odds ratio, CI confidence interval, CNV copy number variation, CN copy number