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Key research area
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Knowledge Gap on extra-genital CT and NG infections in women and MSM
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Morbidity
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Proctitis in anorectal infections
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Reproductive morbidity (women)
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Efficacy control strategies: Treatment
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Efficacy of treatment for both extra-genital and genital infections and associated factors (including treatment resistance, tissue absorption, duration of treatment to account for CT life cycle phases)
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Efficacy control strategies: Re-testing, partner management
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Efficacy of strategies to manage extra-genital infections (including strategies that are already taken to manage genital infections)
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Transmission
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Transmission risk between sexual partners and associated factors, such as bacterial load, sexual behavior
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Self-infection, i.e. transmission risk between anatomic sites within a patient and associated factors, i.e. bacterial load, sexual behavior (women)
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Role in the transmission of other STI including HIV
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Detection
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Microbiologic specifics of a CT - NAAT detection such as bacterial load, viability or other possible markers of transmission or of morbidity
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Testing policy
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Cost effectiveness of extra-genital CT and NG testing taking into account the key research area’s of efficacy of extra-genital control-strategies, transmission and morbidity
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