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Table 2 a,b,c Regression and non-regression in CIN III according to different time intervals

From: CIN III lesions and regression: retrospective analysis of 635 cases

a Biopsy—cone intervals using 33 % percentile of this study
Follow-up 0–6.1 weeks 6.14–12 weeks >12 weeks Total
Non-Regression 215 (34.3 %) 210 (33.5 %) 202 (32.2 %) 627 (98.74 %)
Regression 0 (0 %) 2 (0.9 %) 6 (2.9 %) 8 (1.26 %)
Total 215 (33.8 %) 212 (33.4 %) 208 (32.8 %) 635 (100 %)
b Biopsy—cone intervals according to Munk et. al. ([8])
Follow-up 0–5.4 weeks 5.4–8.9 weeks >8.9 weeks Total
Non-Regression 180 (100 %) 141 (100 %) 306 (97.45 %) 627 (98.74 %)
Regression 0 0 8 (2.55 %) 8 (1.26 %)
Total 180 (28.35 %) 141 (22.2 %) 314 (49.44 %) 635 (100 %)
c Biopsy—cone intervals according to Trimble et al. [9, 16]
Follow-up <15 weeks ≥15 weeks Total
Non-Regression 504 (99.21 %) 123 (96.85 %) 627 (98.74 %)
Regression 4 (0.79 %) 4 (3.15 %) 8 (1.26 %)
Total 508 (80.0 %) 127 (20.0 %) 635 (100 %)
  1. a) three groups each representing a 33 % percentile of the time intervals of this study. 6 of 8 regression cases were observed in the group with intervals longer than 12 weeks, representing 2.9 % in this subgroup. b) Time intervals were chosen exactly as published by Munk et. al. to enable a direct comparison. All regression cases occurred in the longest interval group. The regression rate in this subgroup was lower than in any of the intervals investigated in the study of Munk et al. c) An analysis of only those cases showing an interval of 15 weeks or longer makes it possible to compare the regression rates with the data of Trimble et. al. [9, 16]. Our study found 3.15 % of regression among 127 cases evaluated in this subgroup