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Table 1 635 cases were investigated. 627 showed no regression, i.e. persistence of CIN III (n = 576; 90.7 %), persistence of CIN II (n = 39; 6.1 %) or invasive carcinoma (progression or more likely missed by the previous biopsy: n = 12; 1.9 %). Eight cases showed regression according to our definition, six of them with the diagnosis of CIN I (0.94 %), one showing koilocytosis of the tissue without dysplasia (0.16 %) and one showing inflammation only (0.16 %). Mean size of biopsy was slightly smaller in the eight regression cases and slightly larger in the carcinomas. The few cases with regression and carcinoma had larger sizes of cone biopsies and the patients were on average older. The small numbers of the latter two subgroups result in a reduced significance for analytical purposes

From: CIN III lesions and regression: retrospective analysis of 635 cases

  Size of biopsy (max) Diameter cone (max) Thickness cone (max) Interval in weeks Age
All cases / n = 635
 ‐ mean 5.46 18.3 10.8 11.25 33.3
 ‐ SD 1.44 4.13 4.57 9.73 8.05
 ‐ median 5.0 18.0 10.0 8.86 32.0
Non-regression / n = 627
 ‐ mean 5.46 18.31 10.81 11.17 33.25
 ‐ SD 1.44 4.14 4.58 9.72 8.07
 ‐ median 5.0 18.0 10.0 8.86 32.0
Regression / n = 8
 ‐ mean 5.25 19.13 13.13 18.1 36.0
 ‐ SD 1.51 3.27 4.02 8.53 6.05
 ‐ median 5.0 19.5 12.0 15.93 38.0
Carcinomas / n = 12
 ‐ mean 5,75 20.83 15.83 5.89 39.33
 ‐ SD 2.18 3.32 5.39 5.8 13.24
 ‐ median 5.0 21.5 15.5 3.85 36.0