Table 3 Drugs conferring risk of haemolysis
Potentially haemolytic drugs | Drugs with possible risk of haemolysis | drugs with doubtful risk of haemolysis | Drugs that may increase the exposure of primaquine, chloroquine, piperaquine and lumefantrine metabolism by inhibiting the cytochrome (CYP) 450: | The following drugs may decrease the exposure of primaquine, chloroquine, piperaquine and lumefantrine metabolism by inducing CYP 450: |
|---|---|---|---|---|
Dapsone | Ciprofloxacin | Chloramphenicol | Ketoconazole | Barbiturates |
Sulphonamides | Norfloxacin | Quinine | Itraconazole | Carbamazepine |
Methylene blue | Chloroquine | Cimetidine | Phenytoin | |
Nalidixic acid | Grapefruit juice | Rifampicin | ||
Nitrofurantoin | Erythromycin | Macrolide antibiotics | ||
Niridazole | Ritonavir | Glucocorticoids | ||
Aspirin | ||||
Traditional medicines |