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Table 3 Multinomial logistic regression of factors associated with treatment outcomes in HIV-positive TB patients

From: The impact of HIV status and antiretroviral treatment on TB treatment outcomes of new tuberculosis patients attending co-located TB and ART services in South Africa: a retrospective cohort study

 

Defaulted vs. Successa

Died vs. Successa

Defaulted vs. Successa

Died vs. Successa

 

Unadjusted OR (95 % CI)

Unadjusted OR (95 % CI)

Adjusted OR (95 % CI)

Adjusted OR (95 % CI)

Age, years

1.00 (0.97–1.03)

1.04* (1.01–1.09)

1.00 (0.96–1.03)

1.05* (1.01–1.10)

Gender

Male

Ref.

Ref.

Ref.

Ref.

Female

0.74 (0.41–1.34)

1.08 (0.48–2.41)

0.75 (0.40–1.40)

1.65 (0.66–4.11)

Type of TB

EPTB

Ref.

Ref.

Ref.

Ref.

Smear-negative PTB

1.21 (0.59–2.45)

1.13 (0.44–2.87)

1.05 (0.51–2.18)

0.74 (0.26–2.07)

Smear-positive PTB

0.97 (0.46–2.05)

0.92 (0.34–2.47)

0.85 (0.40–1.82)

0.68 (0.23–2.01)

CD4 count, cells/μL

<50

Ref.

Ref.

Ref.

Ref.

50–199

0.73 (0.32–1.67)

0.43 (0.16–1.11)

0.79 (0.34–1.85)

0.42 (0.15–1.17)

200–349

0.88 (0.36–2.19)

0.31 (0.09–1.06)

0.84 (0.33–2.15)

0.20* (0.05–0.75)

≥350

1.20 (0.41–3.48)

0.39 (0.08–1.91)

0.84 (0.26–2.68)

0.14* (0.03–0.77)

ART status

HIV-positive on ART

Ref.

Ref.

Ref.

Ref.

HIV- positive not on ART

2.26** (1.23–4.14)

4.53*** (2.03–10.10)

2.27* (1.15–4.47)

7.38*** (2.95–18.47)

  1. Ref. reference, EPTB extra-pulmonary tuberculosis, OR odds ratio, 95 % CI 95 % confidence intervals
  2. * p < .05, ** p < .01, *** p < .001
  3. aSuccess defined as cured and treatment completed