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Fig. 3 | BMC Infectious Diseases

Fig. 3

From: Monocyte unresponsiveness and impaired IL1β, TNFα and IL7 production are associated with a poor outcome in Malawian adults with pulmonary tuberculosis

Fig. 3

IL1β and TNFα production in response to stimulation with H37Rv and LPS immediately prior to the start of TB treatment and at the end of the intensive phase, in 6 patients who had a life-threatening clinical deterioration (poor) with controls matched by age, sex, HIV status and CD4 count who had an uneventful clinical course. There was significant restoration of the depressed IL1β responses in parallel with clinical recovery (p = 0.04), with a trend towards restoration of TNFα response (0.18)

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